Neuroleptic Malignant Syndrome
NEEDS IMMEDIATE MEDICAL ATTENTION!
Neuroleptic malignant syndrome (NMS) is a life-threatening idiosyncratic reaction to antipsychotic drugs characterized by fever, altered mental status, muscle rigidity, and autonomic dysfunction.
Cluster Number:
Wiki Number: PW132
Diagnosis: Neuroleptic Malignant Syndrome-NEEDS IMMEDIATE MEDICAL ATTENTION!
US Patients:
World Patients:
Sex Ratio: M+;F
Age Onset:
Brain Area:
Symptoms: increased body temperature, confusion, sweating, rigid muscles, antonomic imbalance: can be fatal within 3 days!
Progression: TOO COMPLEX TO SUMMARIZE HERE!
Causes: Responses to neuroleptic or antipsychotic medicines – 10% CAN BE FATAL! (Includes rapid decrease in “L-Dopa” used for Parkinson’s)
Medications:
Therapies:
Youtube Video: Neuroleptic Malignant Syndrome
Amazon or Library Book:
Neuroleptic Malignant Syndrome and Related Conditions
Click the book to link or buy from Amazon.
Support Group: nmsis.org; 607-674-7920
(Neuroleptic Malignant Syndrome Information Service, Inc.)
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Haloperidol-Induced Neuroleptic Malignant Syndrome: A Case Reportby Jordan P Fader on April 30, 2024
Neuroleptic malignant syndrome (NMS) is a severe reaction to antipsychotic medications characterized by fever, muscle rigidity, altered mental status, and autonomic dysfunction. Here, we describe the case of a 58-year-old female who presented with altered mental status two days after open reduction and internal fixation of the hip. A rapid response team was called when the patient appeared agitated with increased respiratory demand. After being intubated and moved to the ICU, she became febrile...
- Serious adverse drug events associated with psychotropic treatment of bipolar or schizoaffective disorder: a 17-year follow-up on the LiSIE retrospective cohort studyby Petra Truedson on April 18, 2024
INTRODUCTION: Mood stabilisers and other psychotropic drugs can lead to serious adverse drug events (ADEs). However, the incidence remains unknown. We aimed to (a) determine the incidence of serious ADEs in patients with bipolar or schizoaffective disorders, (b) explore the role of lithium exposure, and (c) describe the aetiology.
- Neuroleptic Malignant Syndrome: An Intensive Care Unit Case of Exceptionally High Creatinine Kinase and Myoglobin Levelsby Eduardo Macedo on April 17, 2024
Neuroleptic Malignant Syndrome (NMS) is a rare, life-threatening neurologic emergency known to be related to the administration or sudden withdrawal of dopaminergic medications. The clinical course, symptoms, and bloodwork are very heterogeneous, making this syndrome difficult to identify. Thus, NMS is a diagnosis of exclusion. We present a case of severe NMS with exceptionally high creatinine kinase (CK) and myoglobin levels with unclear etiology and a challenging differential diagnosis. Also,...
- Aripiprazole-induced quasi-neuroleptic malignant syndrome: two case reportsby Abdelgadir Hussein M Osman on April 17, 2024
CONCLUSION: Though aripiprazole use is less likely to cause neuroleptic malignant syndrome, on rare occasions it can produce massive symptomatic or asymptomatic increase in serum creatine kinase enzyme levels, raising the need for close monitoring, especially at the initial doses of the drug.