Neuroleptic Malignant Syndrome
NEEDS IMMEDIATE MEDICAL ATTENTION!
Neuroleptic malignant syndrome (NMS) is a life-threatening idiosyncratic reaction to antipsychotic drugs characterized by fever, altered mental status, muscle rigidity, and autonomic dysfunction.
Cluster Number:
Wiki Number: PW132
Diagnosis: Neuroleptic Malignant Syndrome-NEEDS IMMEDIATE MEDICAL ATTENTION!
US Patients:
World Patients:
Sex Ratio: M+;F
Age Onset:
Brain Area:
Symptoms: increased body temperature, confusion, sweating, rigid muscles, antonomic imbalance: can be fatal within 3 days!
Progression: TOO COMPLEX TO SUMMARIZE HERE!
Causes: Responses to neuroleptic or antipsychotic medicines – 10% CAN BE FATAL! (Includes rapid decrease in “L-Dopa” used for Parkinson’s)
Medications:
Therapies:
Youtube Video: Neuroleptic Malignant Syndrome
Amazon or Library Book:
Neuroleptic Malignant Syndrome and Related Conditions
Click the book to link or buy from Amazon.
Support Group: nmsis.org; 607-674-7920
(Neuroleptic Malignant Syndrome Information Service, Inc.)
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Atypical Presentation of Ziprasidone-Induced Neuroleptic Malignant Syndrome: A Case Reportby John Allonce on July 24, 2024
Neuroleptic malignant syndrome (NMS) is a severe adverse reaction associated with neuroleptic or antipsychotic drugs. This case report discusses a 43-year-old man with a history of bipolar disorder and polysubstance abuse who presented with altered mental status, autonomic dysfunction, and muscular rigidity. The patient had recently started on ziprasidone, a second-generation antipsychotic, leading to an atypical presentation of NMS. Unlike classic findings associated with NMS induced by...
- Integrating Physiotherapy in Neuroleptic Malignant Syndrome Management: A Case Reportby Nikita H Seth on July 23, 2024
Neuroleptic malignant syndrome (NMS) is a rare but potentially fatal condition characterized by hyperthermia, autonomic dysregulation, altered mental status, and muscular rigidity. It typically results from the blockade of dopamine receptors by antipsychotic medications. We present the case of a 70-year-old female who developed NMS after non-compliant use of clozapine. She presented with symptoms including irrelevant talk, breathlessness, and generalized muscle weakness. On examination, she was...
- Catatonia: A Narrative Review for Hospitalistsby Alyssa C Smith on July 22, 2024
CONCLUSIONS: With greater knowledge about catatonia, internists are uniquely positioned to recognize and initiate treatment.
- Concomitant Administration of Ozanimod and Serotonergic Antidepressants in Patients With Ulcerative Colitis or Relapsing Multiple Sclerosisby Miguel Regueiro on July 17, 2024
CONCLUSIONS: No evidence of increased TEAEs potentially associated with serotonin accumulation was observed with concurrent use of ozanimod and SSRIs/SNRIs.