Neuroleptic Malignant Syndrome
NEEDS IMMEDIATE MEDICAL ATTENTION!
Neuroleptic malignant syndrome (NMS) is a life-threatening idiosyncratic reaction to antipsychotic drugs characterized by fever, altered mental status, muscle rigidity, and autonomic dysfunction.
Cluster Number:
Wiki Number: PW132
Diagnosis: Neuroleptic Malignant Syndrome-NEEDS IMMEDIATE MEDICAL ATTENTION!
US Patients:
World Patients:
Sex Ratio: M+;F
Age Onset:
Brain Area:
Symptoms: increased body temperature, confusion, sweating, rigid muscles, antonomic imbalance: can be fatal within 3 days!
Progression: TOO COMPLEX TO SUMMARIZE HERE!
Causes: Responses to neuroleptic or antipsychotic medicines – 10% CAN BE FATAL! (Includes rapid decrease in “L-Dopa” used for Parkinson’s)
Medications:
Therapies:
Youtube Video: Neuroleptic Malignant Syndrome
Amazon or Library Book:
Neuroleptic Malignant Syndrome and Related Conditions
Click the book to link or buy from Amazon.
Support Group: nmsis.org; 607-674-7920
(Neuroleptic Malignant Syndrome Information Service, Inc.)
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- A real-world pharmacovigilance study of neuroleptic malignant syndrome based on FDA adverse event reporting systemby Yu Zhang on December 26, 2024
CONCLUSION: The current comprehensive pharmacovigilance study identified more drugs associated with NMS and provides references to clinicians for clinical practice. Also, further research is needed to investigate the causal relationship between these drugs and NMS.
- The limited clinical utility of a routine creatine kinase (CK) on admission to a psychiatric inpatient unitby Fraser A M Scott on December 19, 2024
CONCLUSIONS: The clinical utility of untargeted screening using a serum CK for psychiatric inpatients appears limited, with poor specificity in detection of NMS and a minimal impact on subsequent clinical management.
- Diagnostic Challenges in Malignant Hyperthermia and Anesthesia-Induced Rhabdomyolysis: A Case Studyby Maya Belitova on December 15, 2024
BACKGROUND Malignant hyperthermia (MH) and anesthesia-induced rhabdomyolysis (AIR) are rare, yet life-threatening complications that need prompt therapeutic actions and logistic preparedness for treatment success. Both conditions are triggered by general anesthetics, particularly volatiles and depolarizing muscle relaxants. In comparison with MH, which is an inherited pharmacogenomic disease of calcium channel receptor subpopulation and arises only after trigger exposure, AIR has been described...
- Inflammation-Related Non-Infectious Febrile Reaction Induced by Electroconvulsive Therapy in a Young Female with Bipolar Disorder: A Case Report and Literature Reviewby Chia-Chi Lin on December 4, 2024
Electroconvulsive therapy (ECT) has been employed as an effective treatment for refractory psychiatric disorders worldwide. Despite its extensive use, the occurrence of a fever following ECT has been rare and seldom documented. The reasons behind a post-ECT fever could vary; instances solely attributed to inflammation have been scarcely reported. We present the case of a 27-year-old woman diagnosed with bipolar disorder who experienced multiple fever episodes after having ECT. Diagnostic tests...