Major Depressive Episode
Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest. Also called major depressive disorder or clinical depression, it affects how you feel, think and behave and can lead to a variety of emotional and physical problems. You may have trouble doing normal day-to-day activities, and sometimes you may feel as if life isn’t worth living.
More than just a bout of the blues, depression isn’t a weakness and you can’t simply “snap out” of it. Depression may require long-term treatment. But don’t get discouraged. Most people with depression feel better with medication, psychotherapy or both.
Cluster Number:
Wiki Number: PW116
Diagnosis: Major Depressive Episode
US Patients: If untreated can last for several months to two years. Symptoms may improve within 6-8 weeks with treatment.
World Patients:
Sex Ratio: M+;F
Age Onset: Ages 20-45
Brain Area:
Symptoms: Symptoms for two weeks of major depressive disorder: loss of interest or pleasure, anxiety, insomnia
Progression: saddened mood, poor sleep, loss of energy, concentration or appetite, thoughts of death or suicide
Causes: Neurotransmitters out of balance, feeling worthless and dispairing; heredity or familial causes
Medications: antidepressants which take 4-6 weeks until maximum effect;
Therapies: psychotherapy
Youtube Video: Major Depressive Episode Self-Care Strategies
Amazon or Library Book:
Handbook of Depression in Children and Adolescents
Click the book to link or buy from Amazon. (Very Expensive!)
Your content goes here. Edit or remove this text inline or in the module Content settings. You can also style every aspect of this content in the module Design settings and even apply custom CSS to this text in the module Advanced settings.
Support Group:adaa.org/supportgroups; Online
(Anxiety & Depression Association of America)
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Brain-derived Neurotrophic Factor and High Sensitive C-reactive Protein in Bipolar Depression and Unipolar Depression: The Practical Usage as a Discriminatory Toolby Shima Shahyad on January 26, 2023
CONCLUSION: Patients suffering from BD had lowest BDNF levels compared to MDD or healthy adults and this biomarker could play a practical role differentiating MDD from BD. Several studies are required confirming our outcomes.
- Lipid Alteration Signature in the Blood Plasma of Individuals With Schizophrenia, Depression, and Bipolar Disorderby Anna Tkachev on January 25, 2023
CONCLUSIONS AND RELEVANCE: In this study, SCZ was accompanied by a reproducible profile of plasma lipidome alterations, not associated with symptom severity, medication, and demographic and environmental variables, and largely shared with BPD and MDD. This lipid alteration signature may represent a trait marker of severe psychiatric disorders, indicating its potential to be transformed into a clinically applicable testing procedure.
- Pursuing personalized medicine for depression by targeting lateral or medial prefrontal cortex with deep TMSby Abraham Zangen on January 24, 2023
CONCLUSION: This study provides a new treatment option for MDD, using the H7 Coil, and initial guidance to differentiate between patients likely to respond to LPFC versus MPFC stimulation targets, which require further validation studies.
- Rates and predictors of mental health care utilisation in patients following a prolonged stay on intensive care unit: a prospective cohort studyby Gloria-Beatrice Wintermann on January 24, 2023
CONCLUSION: Every fourth patient surviving prolonged ICU treatement makes use of mental healthcare . Particularly male patients with pre-existing mental disorders should be targeted preventively, receiving specific psychoeducation about psychological long-term sequelae and mental healthcare options post-ICU.Trial registration numberDRKS00003386.