Major Depressive Episode
Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest. Also called major depressive disorder or clinical depression, it affects how you feel, think and behave and can lead to a variety of emotional and physical problems. You may have trouble doing normal day-to-day activities, and sometimes you may feel as if life isn’t worth living.
More than just a bout of the blues, depression isn’t a weakness and you can’t simply “snap out” of it. Depression may require long-term treatment. But don’t get discouraged. Most people with depression feel better with medication, psychotherapy or both.
Cluster Number:
Wiki Number: PW116
Diagnosis: Major Depressive Episode
US Patients: If untreated can last for several months to two years. Symptoms may improve within 6-8 weeks with treatment.
World Patients:
Sex Ratio: M+;F
Age Onset: Ages 20-45
Brain Area:
Symptoms: Symptoms for two weeks of major depressive disorder: loss of interest or pleasure, anxiety, insomnia
Progression: saddened mood, poor sleep, loss of energy, concentration or appetite, thoughts of death or suicide
Causes: Neurotransmitters out of balance, feeling worthless and dispairing; heredity or familial causes
Medications: antidepressants which take 4-6 weeks until maximum effect;
Therapies: psychotherapy
Youtube Video: Major Depressive Episode Self-Care Strategies
Amazon or Library Book:
Handbook of Depression in Children and Adolescents
Click the book to link or buy from Amazon. (Very Expensive!)
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Support Group:adaa.org/supportgroups; Online
(Anxiety & Depression Association of America)
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Differentiating Stages of Bipolar and Unipolar Depression-The Possible Role of sICAM-1 and sVCAM-1by Maja Pantovic-Stefanovic on July 26, 2024
Increased immune-inflammatory activation has been repeatedly linked to etiopathogenesis and the progression of both major depressive disorder (MDD) and bipolar depression (BD). We explore the role of soluble intercellular cell adhesion molecule-1 (sICAM-1) and soluble vascular cell adhesion molecule-1 (sVCAM-1) in diagnostic differentiation and disorder progression in patients with MDD and BD. Serum levels of sICAM-1 and sVCAM-1 were measured in 137 patients (MDD = 93 and BD = 44) and compared...
- Resilience as a protective factor against depression in informal caregiversby Fernando L Vázquez on July 25, 2024
INTRODUCTION: Although previous research has demonstrated that resilience can be protective against various mental health conditions such as depression, existing studies examining the relationship between resilience and depression have limitations. To our knowledge, the moderators of the relationship have not been examined. The aim of this study was to determine whether resilience acts as a protective factor against depression in informal caregivers and to examine potential moderators of the...
- Prevalence and clinical correlates of abnormal lipid metabolism in older Chinese patients with first-episode drug-naive major depressive disorderby Xiao Huang on July 25, 2024
CONCLUSION: The importance of regular lipid assessment in older MDD patients needs to be taken into account.
- Antenatal and postpartum depression in women who conceived after infertility treatment: a longitudinal studyby Yuka Ito on July 24, 2024
CONCLUSION: Women conceiving through infertility treatment were not found to have a higher risk of diagnosable perinatal depressive disorder than those conceiving naturally. However, a history of infertility treatment can marginally increase sub-clinical postpartum depressive symptoms.