Major Depressive Episode
Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest. Also called major depressive disorder or clinical depression, it affects how you feel, think and behave and can lead to a variety of emotional and physical problems. You may have trouble doing normal day-to-day activities, and sometimes you may feel as if life isn’t worth living.
More than just a bout of the blues, depression isn’t a weakness and you can’t simply “snap out” of it. Depression may require long-term treatment. But don’t get discouraged. Most people with depression feel better with medication, psychotherapy or both.
Cluster Number:
Wiki Number: PW116
Diagnosis: Major Depressive Episode
US Patients: If untreated can last for several months to two years. Symptoms may improve within 6-8 weeks with treatment.
World Patients:
Sex Ratio: M+;F
Age Onset: Ages 20-45
Brain Area:
Symptoms: Symptoms for two weeks of major depressive disorder: loss of interest or pleasure, anxiety, insomnia
Progression: saddened mood, poor sleep, loss of energy, concentration or appetite, thoughts of death or suicide
Causes: Neurotransmitters out of balance, feeling worthless and dispairing; heredity or familial causes
Medications: antidepressants which take 4-6 weeks until maximum effect;
Therapies: psychotherapy
Youtube Video: Major Depressive Episode Self-Care Strategies
Amazon or Library Book:
Handbook of Depression in Children and Adolescents
Click the book to link or buy from Amazon. (Very Expensive!)
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Support Group:adaa.org/supportgroups; Online
(Anxiety & Depression Association of America)
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Altered dynamic functional connectivity in antagonistic state in first-episode, drug-naive patients with major depressive disorderby Min Wang on December 19, 2024
CONCLUSIONS: Our study highlights the altered dynamics of the antagonistic state as a fundamental aspect of disrupted FNC in early MDD.
- The impact of a coach-guided personalized depression risk communication program on the risk of major depressive episode: study protocol for a randomized controlled trialby JianLi Wang on December 19, 2024
BACKGROUND: Depression is a highly prevalent and disabling mental health problem. Self-help has been strongly advocated for dealing with depression. Built upon the research on risk prediction modeling and risk communication, we developed a coach-guided, personalized depression risk communication tool (PDRC) for sharing information about individualized depression risk and evidence-based self-help strategies. The primary objective of this project is to evaluate the impact of the PDRC on the...
- Newly estimated disability weights for 196 health states in Hubei Province, Chinaby Mengge Zhou on December 19, 2024
CONCLUSIONS: The burden of mental disorders among Hubei residents, especially moderate or severe major depressive disorder, deserves further attention. When using different anchoring methods, DW rankings were maintained relatively stable rather than the absolute values in Hubei. Substantial differences of DW rankings between our results and that in China, GBD 2013, and Japan draw attention to the need for deriving local disability for disease burden calculation.
- Traditional Chinese medicine prevents and treats depression by regulating hippocampal neuroplasticity: a reviewby Li-Jun Zhu on December 19, 2024
Depression, a heterogeneous disorder with symptoms involving emotion, cognition, and behavior, is characterized by high morbidity, low treatment acceptance, and recurrent episodes. It is expected to become a major disease in the global healthcare burden by 2030. The pathogenesis of depression is complex, involving genetic, environmental, neurological, immune, endocrine and other factors, among which neuroplasticity plays a key role in the development of depression and antidepressant treatment....