Insomnia is a sleep disorder in which you have trouble falling and/or staying asleep. The condition can be short-term (acute) or can last a long time (chronic). It may also come and go. Acute insomnia lasts from 1 night to a few weeks. Insomnia is chronic when it happens at least 3 nights a week for 3 months or more.
Wiki Number: W106
US Patients: 20-30%
Sex Ratio: M; W2
Brain Area: sleep apnea; hypothalamic-pituitary-adrenal axis – releases cortisol;higher metabolic rates in PET brain scans; heritability
Symptoms: inability to fall or stay asleep; daytime sleepiness, low energy, depressed mood, dangerous lack fo concentration
Causes: alcohol/benzodiazapine/opioid-induced; changes in sex hormones in elderly
Medications: not recommended for more than five weeks;
Therapies: sleep hygiene = consistent bedtime; quiet and dark room, and regular exercise. CBT; overnight sleep study
4 CURRENT ARTICLES
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Utilizing network pharmacology and experimental validation to explore the potential molecular mechanisms of BanXia-YiYiRen in treating insomniaby Liang Wang on January 24, 2022
BanXia-YiYiRen (Pinellia Ternata and Coix Seed, BX-YYR) has been clinically proven to be an effective Chinese medicine compatible with the treatment of insomnia. However, the underlying mechanism of BX-YYR against insomnia remains unclear. This study aimed to explore the pharmacological mechanisms of BX-YYR in treating insomnia based on network pharmacology and experimental validation. The drug-disease targets were obtained using publicly available databases. The analysis revealed 21 active...
- Medical cannabis oil for benign essential blepharospasm: a prospective, randomized controlled pilot studyby Ofira Zloto on January 24, 2022
CONCLUSIONS: Medical cannabis can be an effective and safe treatment for BEB as a second line after BTX-A injections when used for 3 months. No significant ocular or systemic side effects was associated with the treatment.
- Sleep, Positive Affect and Circulating Interleukin-6 in Women with Temporomandibular Joint Disorderby Carly Hunt on January 24, 2022
CONCLUSIONS: The potential salutary effects of PA on resting IL-6 erode when sleep is poor, underscoring the importance of considering sleep in conceptual and intervention models of TMD.
- Associations Between the 2011 Great East Japan Earthquake and Tsunami and the Sleep and Mental Health of Japanese People: A 3-Wave Repeated Surveyby Yu Itoh on January 24, 2022
CONCLUSION: This study demonstrated that the prevalence of insomnia was significantly higher after the earthquake. Moreover, individuals with insomnia were more likely to experience psychological distress after the earthquake that continued until 2012.