Obsession with the idea of having a serious but undiagnosed medical condition.
Hypochondriasis usually develops during adulthood.
Symptoms include a long-term and intense fear of having a serious condition and worry that minor symptoms indicate something serious. A person may frequently visit or switch doctors.
Counseling and medications may help.


Cluster Number:
Wiki Number: W100
Diagnosis: Hypochondrasis-Hypochondria
US Patients: About 5%
World Patients:
Sex Ratio:
Age Onset: Age 4
Brain Area:
Symptoms: preoccupation with developing a serious illness even after medical assurance they do not;”white-coat-syndrome” results
Progression: may avoid medical personnel through lack of trust
Causes: 10%-37% heritable; over-protective care-givers and focus on minor health problems
Medications: antidepressants help 50%’;
Therapies: CBT-Counseling


The world-wide medical research
reports chosen for each diagnosis 

Clicking each title opens the
PubMed article’s summary-abstract.

  • Platelet Parameters, C-Reactive Protein, and Depression: An Association Study
    by Jin-Min Wang on January 13, 2022

    CONCLUSION: Classical platelet parameters (PLT, MPV, PCT, PDW) and CRP were shown to be associated with specific depressive symptoms and cognitive impairment factors, including sleep, gastrointestinal symptoms, hypochondriasis, losing interest in work, and despair. These results suggest that both platelet parameters and CRP could be suitable biomarkers for predicting the occurrence and prognosis of depression, thus providing a new target for its treatment.

  • Self-induced hemopericardium using a syringe needle: A rare method of suicide
    by Sarathchandra Kodikara on January 6, 2022

    This communication highlights a rare case of suicide by self-induced hemopericardium caused by a penetrating syringe needle. A 20-year-old male, diagnosed with ulcerative colitis, severe depression and hypochondriasis, was found dead at home. There was a 23-gauge 3 cm long syringe needle, connected to a 3 cc barrel, penetrating the left side of the chest. Autopsy revealed 3 fresh puncture marks on the left side of the anterior chest with subcutaneous hemorrhage underlying the puncture marks. The...

  • Illness Anxiety Disorder
    by Jennifer H. French on January 1, 2022

    Illness anxiety disorder (previously called hypochondriasis, a term which has been revised in the DSM-5 due to its disparaging connotation) is a psychiatric disorder defined by excessive worry about having or developing a serious undiagnosed medical condition. People with an illness anxiety disorder (IAD) experience persistent anxiety or fear of developing or having a serious medical illness that adversely affects their daily life. This fear persists despite normal physical examination and...

  • Epidemiological Features and Clinical Manifestations of Patients With Somatoform Disorder at a Tertiary Medical City in Riyadh, Saudi Arabia
    by Abdulkarim O Alanazi on December 27, 2021

    Background Somatoform disorder (SD), known as the presence of physical symptoms suggesting a physical condition, for which there are no demonstrable organic findings or established physiological mechanisms with positive evidence that the symptoms are related to psychological causes. The aim of this study was to highlight the epidemiological characteristics, demographic features, comorbidities, and clinical presentations of patients with SD. Materials and methods This was a retrospective study of...