Hypnotic, or soporific drugs, commonly known as sleeping pills, are a class of psychoactive drugs whose primary function is to induce sleep and for the treatment of insomnia, or for surgical anesthesia. This group is related to sedatives.
Wiki Number: PW199-B
US Patients: Hypnotics induce sleep, treat insomnia, or as surgical anesthesia. They actually disturb sleep, but 95% are described for insomnia in
World Patients: some countries. Most physicians try to change the environment first with better sleep hygiene, reduction of caffeine, or CBT.
Sex Ratio: When prescribed, they should be used for the shortest time necessary. Prescriptions for sleep disorders, as of 2010, 13.7% were
Age Onset: nonbenzodiazapines and 10.8% were benzodiazepines. The neuro-hormone melatonin also has an hypnotic function.
Brain Area: Benzodiazepines should not be used beyond 2-4 weeks, given intermittently at the lowest doses possible, because they disturb
Symptoms: slow wave sleep and after more use will rebound insomnia. Older adult should only use benzodiazepines if other drugs fail.
Progression: The Wikipedia article gives brief descriptions and critiques of other hypnotics. They should not be used at all with older people or
Causes: those with dementia and have other side effects.
4 CURRENT ARTICLES
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PubMed article’s summary-abstract.
- Clinical outcomes of paliperidone long-acting injection in patients with schizophrenia: a 1-year retrospective cohort studyby Hsue-Wei Chan on October 16, 2021
CONCLUSIONS: PLAI reduces the incidence of admission and emergency room visits.
- Review of the International Hypnosis Literatureby Shelagh Freedman on October 15, 2021
- Hypnotisability and the Cerebellum: Hypotheses and Perspectivesby Enrica Laura Santarcangelo on October 15, 2021
Hypnotisability is a multidimensional trait predicting the proneness to enter hypnosis and/or accept suggestions and is associated with several psychophysiological correlates. This scoping review reports the differences between individuals with high (highs) and low hypnotizability (lows) in the left cerebellar lobules IV-VI grey matter volume, in the excitability of the right motor cortex and in motor and non-motor functions in which the cerebellum may be involved. A reduced cerebellar...
- Family of Structurally Related Bioconjugates Yields Antibodies with Differential Selectivity against Ketamine and 6-Hydroxynorketamineby Zhen Zheng on October 15, 2021
The dissociative-hypnotic compound ketamine is being used in an increasingly wide range of therapeutic contexts, including anesthesia, adjunctive analgesia, treatment-resistant depression, but it also continues to be a notable substance of abuse. No specific antidotes exist for ketamine intoxication or overdose. Immunopharmacotherapy has demonstrated the ability to offer overdose protection through production of highly specific antibodies that prevent psychoactive drug penetration across the...