Abnormally increased and sometimes uncontrollable activity or muscular movements. 2 : a condition especially of childhood characterized by hyperactivity


Cluster Number:
Wiki Number: W097
Diagnosis: Hyperkinesia
US Patients:
World Patients:
Sex Ratio:
Age Onset:
Brain Area: The subthalamic nucleus improperly controls the basal ganglia producing these involuntary, unwanted movements.
Symptoms: several variations of excessive, unwanted muscle movements: ataxia, athetosis, chorea, dystonias, hemiballismus,
Progression: hemifacial spasms, myoclonus, stereotypies, tremors, tics, and volitional hyperkinesia; all are subsets of movements
Causes: Oversensitivity of dopamine and norepinephrine receptors or hyperactivity of the dopaminergic receptors appear.
Medications: Vary by diagnosis.
Therapies: Vary by diagnosis.

Youtube Video: Diagnosing and Treating

Hyperkinetic Movement Disorders

Amazon or Library Book: Hyperkinetic Children (Kindle Only)

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The world-wide medical research
reports chosen for each diagnosis 

Clicking each title opens the
PubMed article’s summary-abstract.

  • SLC6A3, HTR2C and HTR6 Gene Polymorphisms and the Risk of Haloperidol-Induced Parkinsonism
    by Gordana Nedic Erjavec on December 23, 2022

    Antipsychotic-induced parkinsonism (AIP) is the most common type of extrapyramidal side effect (EPS), caused by the blockage of dopamine receptors. Since dopamine availability might influence the AIP risk, the dopamine transporter (DAT) and serotonin receptors (5-HTRs), which modulate the dopamine release, may be also involved in the AIP development. As some of the individual differences in the susceptibility to AIP might be due to the genetic background, this study aimed to examine the...

  • Case report: Takotsubo syndrome induced by severe hypoglycemia
    by Panpan Xia on December 8, 2022

    CONCLUSION: This is a representative case of TTS caused by hypoglycemia. Due to the self-limiting nature of TTS, diagnoses can be missed among hypoglycemic patients. Thus, echocardiography is required for patients with hypoglycemia to ensure an accurate TTS diagnosis in the emergency department.

  • Accidental Falls in Patients with Hyperkinetic Movement Disorders: A Systematic Review
    by Carl N Homann on October 28, 2022

    BACKGROUND: The significance of falls and their repercussions in Parkinson's disease has been extensively researched. However, despite potentially serious effects on health and quality of life and negative impact on the healthcare system, there is not a sufficient understanding of the role of falls in hyperkinetic movement disorders (HKMDs). This review aims to provide an overview of the prevalence of falls, injuries, and preventive measures in the most common HKMDs.

  • Molecular Mechanisms of Takotsubo Syndrome
    by Liam S Couch on October 27, 2022

    Takotsubo syndrome (TTS) is a severe but reversible acute heart failure syndrome that occurs following high catecholaminergic stress. TTS patients are similar to those with acute coronary syndrome, with chest pain, dyspnoea and ST segment changes on electrocardiogram, but are characterised by apical akinesia of the left ventricle, with basal hyperkinesia in the absence of culprit coronary artery stenosis. The pathophysiology of TTS is not completely understood and there is a paucity of evidence...