HIV Infection Disorder

Resources for Patients and Caregivers

HIV causes AIDS and interferes with the body’s ability to fight infections.

The virus can be transmitted through contact with infected blood, semen, or vaginal fluids.

Within a few weeks of HIV infection, flu-like symptoms such as fever, sore throat, and fatigue can occur. Then the disease is usually asymptomatic until it progresses to AIDS. AIDS symptoms include weight loss, fever or night sweats, fatigue, and recurrent infections.

No cure exists for AIDS, but strict adherence to anti-retroviral therapy (ART) can dramatically slow the disease’s progress, prevent secondary infections and complications, and prolong life.

Cluster Number:
Wiki Number: 22-HIV Infection Disorder
Diagnosis:
US Patients:
World Patients:
Sex Ratio:
Age Onset:
Brain Area:
Symptoms:
Progression: Life expectancy averages 10 years after HIV infection unless treated.
Causes:HIV-AiDs attacks the immune system leading to progressively less resistance to other infections
Medications:
Therapies:

CLICK HERE FOR THE FULL WIKIPEDIA ARTICLE

Youtube Video: What is HIV and AIDS?

Amazon or Library Book: Enhancing Sexual Health, Self-Identity and Wellbeing among Men Who Have Sex with Men

Click the book to link or order from Amazon.

Support Group: hivaidstherapytribe.com

Narrative Review on the Management of Neck of Femur Fractures in People Living with HIV: Challenges, Complications, and Long-Term Outcomes
by Yashar Mashayekhi on July 30, 2025
Neck of femur (NOF) fractures are a critical orthopaedic emergency with a high morbidity and mortality prevalence, particularly in people living with Human Immunodeficiency Virus (PLWHIV). A combination of HIV infection, combined antiretroviral therapy (cART), and compromised bone health further increases the risk of fragility fractures. Additionally, HIV-related immune dysfunction, cART-induced osteoporosis, and perioperative infection risks further pose challenges in ongoing surgical...
Enhanced humoral and cellular immunogenicity of COVID-19 vaccines in people living with HIV: A real-world analysis
by Tzu-Ping Weng on July 30, 2025
CONCLUSION: Primary-booster mRNA vaccination elicited stronger humoral responses than heterologous regimens in PLWH. However, additional booster vaccines may be necessary for PLWH with low CD4 counts and diminished cellular immunity despite vaccination. These findings highlight the importance of tailored vaccination strategies for the immunocompromised population.
TRIM5α/Cyclophilin A-Modified MDBK Cells for Lentiviral-Based Gene Editing
by Lijing Wo on July 30, 2025
The human immunodeficiency virus 1 (HIV-1)-based lentivirus has been widely used for genetic modification. However, the efficiency of lentiviral-based gene modification in Madin-Darby bovine kidney (MDBK) cells is considerably limited. In this study, we have shown that siRNA-mediated depletion of TRIM5α, a restriction factor in HIV-1 infection, can dramatically enhance HIV-1 infection in MDBK cells. Furthermore, we generated a doxycycline-inducible Cas9-overexpressing MDBK cell line (MDBK-iCas9)...
Immune-Pathological Correlates of Disease Severity in New-World Kala-Azar: The Role of Parasite Load and Cytokine Profiles
by Ingridi de Souza Sene on July 30, 2025
Kala-azar is a protracted disease caused by the protozoan Leishmania infantum (zoonotic) or L. donovani (anthroponotic), transmitted by sandflies. Patients present with fever, anemia, and hepatosplenomegaly, potentially progressing to hemorrhaging, secondary infections, and death. Its pathogenesis is linked to an exaggerated cytokine response. We studied 72 hospitalized patients, analyzing clinical data and outcomes in relation to L. infantum DNA loads in blood and bone marrow, and plasma...