General Adaptation Syndrome
The general adaptation syndrome (GAS), developed by Hans Selye, describes the pattern of responses that the body goes through after being prompted by a stressor. There are three stages: alarm, resistance, and exhaustion.
Wiki Number: W089
Diagnosis: General Adaptation Syndrome
Brain Area: amygdala, hypothalamus, limbic system, stria terminalis, prefrontal cortex; the autonomic nervous system takes over
Symptoms: lack of coping resources to chronic stress can lead to delusions, depression and anxiety, raise serum lipids vs. heart attacks
Progression: alarm(shock&(antishock-locus coeruleus); resistancea, and exhaustion-return to homeostaisis unless chronic-PTSD
Causes: sympathetic nervous system (like “speech anxiety”) and the hypothalmic nervous system-fight-flight releasing cortisol
Medications: None Listed
Therapies: Learning coping strategies reduces stress;acute stress, short duration; (may be milder) stress, long enough to be chronic
Youtube Video: Stress and the HPA Axis
Amazon or Library Book: Human Adaptation to Extreme Stress
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4 CURRENT ARTICLES
The world-wide medical research
reports chosen for each diagnosis
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PubMed article’s summary-abstract.
- Fibromyalgia Syndrome Pain in Men and Women: A Scoping Reviewby Ilga Ruschak on January 21, 2023
Fibromyalgia syndrome (FMS) is a chronic musculoskeletal disorder of unknown etiology that affects up to 5.0% of the world population. It has a high female predominance, between 80 and 96%. Due to the low number of diagnosed men, research work has focused mainly on women. The extensive body of literature on sex differences in pain in the general population suggests that men and women differ in their responses to pain, with greater sensitivity to pain and a higher risk of clinical pain commonly...
- The effect of hepatocyte growth factor on intestinal adaption in an experimental model of short bowel syndromeby George Bagias on January 11, 2023
CONCLUSION: HGF emerges as a growth factor that enhances intestinal adaptation. The future use of HGF may potentially reduce the requirement for PN in SBS patients.
- Psychosocial Factors Associated with Burnout and Self-Perceived Health in Spanish Occupational Therapistsby Rubén Juy on January 8, 2023
(1) Background: There are few studies of burnout syndrome (BS) in occupational therapists (OTs), and protective factors for BS have received little attention in the scientific literature. This research aimed to estimate the prevalence of BS, characterize the associated psychosocial factors, and analyze their relationship with health in a sample of Spanish OTs. (2) Methods: A total of 127 therapists completed the Maslach Burnout Inventory (MBI) and other standardized questionnaires measuring:...
- Risk of Poor Neonatal Adaptation Syndrome Among Infants Exposed to Second-Generation Atypical Antipsychotics Compared to Antidepressants: Results From the National Pregnancy Registry for Psychiatric Medicationsby Adele C Viguera on January 5, 2023
Objective: While poor neonatal adaptation syndrome (PNAS) has been particularly well described among infants exposed to antidepressants, specifically selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), this is not the case for second-generation antipsychotics (SGAs). In 2011, the US Food and Drug Administration (FDA) issued a drug safety warning regarding fetal antipsychotic exposure and risk for PNAS and extrapyramidal symptoms (EPS). The...