Dyscalculia is a math learning disability that impairs an individual’s ability to learn number-related concepts, perform accurate math calculations, reason and problem solve, and perform other basic math skills. 1. Dyscalculia is sometimes called “number dyslexia” or “math dyslexia.”


Cluster Number:
Wiki Number: W071
Diagnosis: Dyscalculia (Math Abilities)
US Patients: 3-6%
World Patients:
Sex Ratio:
Age Onset:
Brain Area: intraparietal sulcus, frontal lobe, and left angular gyrus; difficulty with spatial awareness and memory
Symptoms: math abilities may stop at the 4th grade level, that may also be a developmental delay
Progression: Limitations in memory, counting, doing math problems, avoidance of careers where math or science is a component
Medications: transcranial direct durrent stimulation of the left parietal (anode) and right parietal lobe (cathode)improved math for 2.
Therapies: Several computerized training programs are listed in the Wikipedia article followed by the article’s bibliography.


The world-wide medical research
reports chosen for each diagnosis 

Clicking each title opens the
PubMed article’s summary-abstract.

  • Mathematical learning deficits originate in early childhood from atypical development of a frontoparietal brain network
    by Ulrike Kuhl on September 30, 2021

    Mathematical learning deficits are defined as a neurodevelopmental disorder (dyscalculia) in the International Classification of Diseases. It is not known, however, how such deficits emerge in the course of early brain development. Here, we conducted functional and structural magnetic resonance imaging (MRI) experiments in 3- to 6-year-old children without formal mathematical learning experience. We followed this sample until the age of 7 to 9 years, identified individuals who developed...

  • Numerical cognition in children with cerebral palsy
    by Silvia Cristina de Freitas Feldberg on September 25, 2021

    Children with Cerebral Palsy (CP) often perform poorly in mathematics. It is not yet clear to what extent mathematics difficulties in this clinical condition are similar to those observed in developmental dyscalculia. To better elucidate this issue, we conducted an exploratory cross-sectional study with a sample of children and adolescents with congenital brain injuries and educational history of problems in Mathematics. Fifty students aged 7-15 years, of both genders (28 males) participated in...

  • Identification of Phonology-Related Genes and Functional Characterization of Broca's and Wernicke's Regions in Language and Learning Disorders
    by Nina Unger on September 20, 2021

    Impaired phonological processing is a leading symptom of multifactorial language and learning disorders suggesting a common biological basis. Here we evaluated studies of dyslexia, dyscalculia, specific language impairment (SLI), and the logopenic variant of primary progressive aphasia (lvPPA) seeking for shared risk genes in Broca's and Wernicke's regions, being key for phonological processing within the complex language network. The identified "phonology-related genes" from literature were...

  • I can't count, but I can beat you playing cards: a case report on autoimmune encephalitis
    by Laura Mori on September 11, 2021

    CONCLUSIONS: In our patient the calculation disorder has proved to be the most relevant problem and the most difficult to treat. Clinicians should consider a careful approach to determine the prognosis of this syndrome because of the wide range of deficits, the need of prolonged treatment and the rate of long-term sequelae.