Down Syndrome
Cluster Number:
Wiki Number: W069
Diagnosis: Down Syndrome
US Patients: 1 in 1000 babies
World Patients: 5 Mil
Sex Ratio:
Age Onset: Ave IQ-50
Brain Area: Also know as Trisomy 21 due to a third set of genes.
Symptoms: Ages 8-9 maximum mental development.
Progression: probability of a Down-born child increases with the age of the parents.
Causes: 3rd copy of Chromosome 21
Medications: None listed.
Therapies: Support and education
Youtube Video: Down Syndrome Journey
Amazon or Library Book:
Mental Wellness in Adults with Down Syndrome
Amazon or Library Book:
Up, Not Down Syndrome
Click the book to link or buy through Amazon.
Click the book to link or buy from Amazon.
Support Group: ndss.org; 800-221-4602
(National Down Syndrome Society)
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Brain volumes, cognitive, and adaptive skills in school-age children with Down syndromeby Rebecca Grzadzinski on December 20, 2024
CONCLUSIONS: Despite children with DS exhibiting lower cognitive skills and smaller brain volume overall than children with ASD, their deficits in Socialization and Daily Living adaptive skills are comparable. Differences in lobar volumes (e.g., Right Frontal GM/WM, Left Frontal WM, and Left and Right Temporal WM) were observed above and beyond overall differences in total volume. The correlation between cerebellum volumes and Daily Living adaptive behaviors in the DS group provides a novel area...
- Burnout syndrome among general practitioners in the Czech Republic: a repeated survey studyby Ladislav Štěpánek on December 20, 2024
CONCLUSIONS: Between 2023 and 2024, the prevalence of burnout among GPs exhibited a modest decline. Nonetheless, it persists at almost 20%. Ensuring a sufficiently dense network of GPs, providing adequate resource allocation, and raising awareness of their importance are essential measures.
- 'The upside-down' healthcare professional students' experiences of delirium: an all-Ireland focus group studyby Gary Mitchell on December 19, 2024
CONCLUSIONS: This study contributes to the existing literature by providing insights into the perspectives of healthcare professional students on delirium care. The findings also highlight the challenging nature of caring for individuals with delirium and the need for improved delirium education and interdisciplinary collaboration.
- Integrating bioinformatics and machine learning to uncover lncRNA LINC00269 as a key regulator in Parkinson's disease via pyroptosis pathwaysby LiLi Ma on December 19, 2024
CONCLUSIONS: This study identifies LINC00269 as a potential contributor to pyroptosis pathways in PD. While further investigation is required to fully elucidate its role, these findings provide new insights into PD pathogenesis and suggest potential avenues for future research on diagnostic and therapeutic targets. The study underscores the importance of integrating bioinformatics with experimental validation in neurodegenerative disease research.