Disruptive Mood Dysregulation Disorder
Disruptive mood dysregulation disorder (DMDD) is a childhood condition of extreme irritability, anger, and frequent, intense temper outbursts. DMDD symptoms go beyond a being a “moody” child—children with DMDD experience severe impairment that requires clinical attention.
Cluster Number:
Wiki Number: W066
Diagnosis: Disruptive Mood Dysregulation Disorder
US Patients: 1.5% children
World Patients:
Sex Ratio:
Age Onset: Child or adolescent
Brain Area: under-activity of the amygdala at judging other’s anger or sadness; medial front gyrus and anterior cingulate cortex – lower
Symptoms: disproportionate irritable or angry moods or several temper outbursts weekly; poor stress regulation; one year or more
Progression: displays persistent anger against people and objects, often have anxiety and depression in later years
Causes: Brain areas above are important for evaluating and regulating negative emotions; poverty and single-parenthood affect it
Medications: antidepressants, antipsychotics and mood stabilizers
Therapies: None listed.
Youtube Video: Treatment Challenges of Impulse Control
Behavioral Disorder
Amazon or Library Book:
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Teach Your Dragon Manners
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4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Executive function in children with disruptive mood dysregulation disorder compared to attention-deficit/hyperactivity disorder and oppositional defiant disorder, and in children with different irritability levelsby Astrid Brænden on January 21, 2023
Addressing current challenges in research on disruptive mood dysregulation disorder (DMDD), this study aims to compare executive function in children with DMDD, children with attention-deficit/hyperactivity disorder (ADHD), and children with oppositional defiant disorder (ODD). We also explore associations between irritability, a key DMDD characteristic, and executive function in a clinical sample regardless of diagnosis. Our sample include children (6-12 years) referred to child psychiatric...
- Dopamine downregulation in novel rodent models useful for the study of postpartum depressionby Millie Rincón-Cortés on January 9, 2023
Postpartum depression (PPD) is the most common psychiatric disorder following childbirth and is characterized by maternal mood disturbances, impaired maternal responses, and disrupted caregiving- all of which negatively impact offspring development. Since PPD has detrimental consequences for both mother and child, clinical and preclinical research has focused on identifying brain changes associated with this disorder. In humans, PPD is linked to dysregulated mesolimbic dopamine (DA) system...
- Selected Biomarkers of Depression: What Are the Effects of Cytokines and Inflammation?by Stefan Harsanyi on January 8, 2023
Depression is one of the leading mental illnesses worldwide and lowers the quality of life of many. According to WHO, about 5% of the worldwide population suffers from depression. Newer studies report a staggering global prevalence of 27.6%, and it is rising. Professionally, depression belonging to affective disorders is a psychiatric illness, and the category of major depressive disorder (MDD) comprises various diagnoses related to persistent and disruptive mood disorders. Due to this fact, it...
- Gut microbiome dysregulation drives bone damage in broiler tibial dyschondroplasia by disrupting glucose homeostasisby Ting-Ting Xu on January 3, 2023
Tibial dyschondroplasia (TD) with multiple incentives is a metabolic skeletal disease that occurs in fast-growing broilers. Perturbations in the gut microbiota (GM) have been shown to affect bone homoeostasis, but the mechanisms by which GM modulates bone metabolism in TD broilers remain unknown. Here, using a broiler model of TD, we noted elevated blood glucose (GLU) levels in TD broilers, accompanied by alterations in the pancreatic structure and secretory function and damaged intestinal...