Depression
A mental health disorder characterized by persistently depressed mood or loss of interest in activities, causing significant impairment in daily life.
Possible causes include a combination of biological, psychological, and social sources of distress. Increasingly, research suggests these factors may cause changes in brain function, including altered activity of certain neural circuits in the brain.
The persistent feeling of sadness or loss of interest that characterizes major depression can lead to a range of behavioral and physical symptoms. These may include changes in sleep, appetite, energy level, concentration, daily behavior, or self-esteem. Depression can also be associated with thoughts of suicide.
The mainstay of treatment is usually medication, talk therapy, or a combination of the two. Increasingly, research suggests these treatments may normalize brain changes associated with depression.
Cluster Number:
Wiki Number: W058
Diagnoses: Depression
US Patients:
World Patients: 300Mil; 4.4%
Sex Ratio: M;W+
Age Onset:
Brain Area:
Symptoms: low mood and aversion to activity; loss of pleasure;
Effects: the leading cause of disability world-wide;
Causes: childhood adversity ,unequal treatment of siblings, abuse; adult work-or-family stress, medical diagnosis, unemployment
Medications: antidepressants should not be used with initial encounters; long-term depression can benefit from medical help
Therapies: exercise, fond memories; self-help books;
Youtube Video: “I’m Fine” Learning to Live with Depression
Amazon or Library Book:
The Upward Spiral
Amazon or Library Book:
The Vulnerable Man
Click the book to link or order from Amazon.
Click the book to link or order from Amazon.
Jim Lohr’s Download, Lifting My Depression, is available for sale
in the “Blue Box” in this website.
You can download this program from the “Blue Box”
in the right column of the website.
Support Group: dsballiance.org; 800-326-3632
(Depression and Bipolar Support Alliance)
Their website has support groups linked by zip-code
and by state; some face-to-face and some online.
Contact your local Social Security office for possible Disability Benefits through their Disability Determination Services, Section 12.04.
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Associated factors with Premenstrual syndrome and Premenstrual dysphoric disorder among female medical students: A cross-sectional studyby Vy Dinh Trieu Ngo on January 26, 2023
CONCLUSION: The prominent risk factors for Premenstrual Syndrome and Premenstrual Dysphoric Disorder were negative Rhesus blood type, menarche age, caffeine consumption, and self-reported depression.
- Digitally Delivered Dietary Interventions for Patients with Eating Disorders Undergoing Family-Based Treatment: Protocol for a Randomized Feasibility Trialby Megan Hellner on January 26, 2023
CONCLUSIONS: This study contributes to existing FBT literature by thoroughly exploring the acceptability of dietary interventions and their influence on weight restoration, an area in which research is sparse.
- Resilience in the Time of COVID-19: Familial Processes, Coping, and Mental Health in Latinx Adolescentsby Gabriela Livas Stein on January 26, 2023
CONCLUSION: Latinx youth who experienced high levels of COVID-19 stress who enacted problem-focused coping fared better across the pandemic. Familial resilience did not carry the same longitudinal benefit but did bolster mental health concurrently. Clinicians should endeavor to buttress familial resilience processes in addition to problem-engaged coping for Latinx youth in treatment.
- FMRP activity and control of Csw/SHP2 translation regulate MAPK-dependent synaptic transmissionby Shannon N Leahy on January 26, 2023
Noonan syndrome (NS) and NS with multiple lentigines (NSML) cognitive dysfunction are linked to SH2 domain-containing protein tyrosine phosphatase-2 (SHP2) gain-of-function (GoF) and loss-of-function (LoF), respectively. In Drosophila disease models, we find both SHP2 mutations from human patients and corkscrew (csw) homolog LoF/GoF elevate glutamatergic transmission. Cell-targeted RNAi and neurotransmitter release analyses reveal a presynaptic requirement. Consistently, all mutants exhibit...