Dementia
Dementia is a collective term used to describe various symptoms of cognitive decline, such as forgetfulness. It is a symptom of several underlying diseases and brain disorders. Dementia is not a single disease in itself, but a general term to describe symptoms of impairment in memory, communication, and thinking.
Cluster Number:
Wiki Number: W055
Diagnosis: Dementia
US Patients:
World Patients: 50 Mil
Sex Ratio:
Age Onset: Age 80+- 50%
Brain Area: hippocampus shrinks; temporal and parietal lobes shrink; the brain degenerates; SPECT & PET show vascular cause.
Symptoms: early signs: handling finances, getting lost, repeating things;later-need help eating, dressing, getting out of bed
Progression: Alzheimer’s=80%; vascular, 20%=blood loss to the brain; Lewy bodies=hallucinations; frontotemporal=language problems
Causes: lewy bodies, frontotemporal dementia;people with dementia average five other chronic diseases; 50% persistent pain
Medications: donepezil, antipsychotics; no medications show a preventative effect
Therapies: exercise helps sustain activities of daily living;music; diets with low saturated fat and good carbohydrates; vitamin D
Youtube Video: Living with
Young-Onset Dementia
Youtube Video: Later Stage Dementia: Brad and Jean’s Story
Book from Amazon or Library: 2022 Dementia Overview
Click the book to link or order from Amazon.
Support Groups: alz.org; This website allows searching for
local associations. (Alzheimer’s Association)
Contact your local Social Security Office for possible Disability benefits through their Disability Determination Service,
Section 12.02.
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- CSF biomarkers for early-onset Alzheimer's disease in Chinese population from PUMCH dementia cohortby Dan Lei on January 26, 2023
INTRODUCTION: Alzheimer's disease (AD) is one of the highly concerned degenerative disorders in recent decades. Though vast amount of researches has been done in various aspects, early-onset subtype, however, needs more investigation in diagnosis for its atypical manifestations and progression process. Fundamental CSF biomarkers of early-onset AD are explored in PUMCH dementia cohort to depict its laboratory characteristics.
- Functional connectivity and mild behavioral impairment in dementia-free elderlyby Maryam Ghahremani on January 26, 2023
CONCLUSION: MBI in dementia-free older adults is associated with reduced FC in networks known to be disrupted in dementia. Our results complement the evidence linking MBI with Alzheimer's disease biomarkers.
- Montreal Cognitive Assessment Predicts the Short-Term Risk of Lewy Body Disease in Isolated REM Sleep Behavior Disorder with Reduced MIBG Scintigraphyby Masayuki Miyamoto on January 26, 2023
CONCLUSIONS: Among IRBD patients with reduced cardiac MIBG accumulation, MoCA-J score of <26 (Mild Cognitive Impairment-Lewy body) and a low sub-item score for delayed recall predicted short-term progression to probable DLB.
- The problematic syndrome of right temporal lobe atrophy: Unweaving the phenotypic rainbowby Christopher R S Belder on January 26, 2023
No abstract