Delusional disorder, previously called paranoid disorder, is a type of serious mental illness called a psychotic disorder. People who have it can’t tell what’s real from what is imagined. Delusions are the main symptom of delusional disorder. They’re unshakable beliefs in something that isn’t true or based on reality.
Wiki Number: W053
Diagnosis: Delusional Disorder
US Patients: 1% of mental health admissions
Sex Ratio: M;W1½
Age Onset: Age 40
Brain Area: neurotransmitters
Symptoms: strong beliefs, despite evidence; psychotic-out of touch with reality; holds them defensively
Progression: Types: erotomanic – another loves me; grandiose, jealous, persecutory, somatic-error on a medical condition or defect.
Causes: genetic; neurotransmitter, familial component
4 CURRENT ARTICLES
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reports chosen for each diagnosis
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PubMed article’s summary-abstract.
- Limbic links to paranoia: increased resting-state functional connectivity between amygdala, hippocampus and orbitofrontal cortex in schizophrenia patients with paranoiaby Sebastian Walther on October 12, 2021
Paranoia is a frequent and highly distressing experience in psychosis. Models of paranoia suggest limbic circuit pathology. Here, we tested whether resting-state functional connectivity (rs-fc) in the limbic circuit was altered in schizophrenia patients with current paranoia. We collected MRI scans in 165 subjects including 89 patients with schizophrenia spectrum disorders (schizophrenia, schizoaffective disorder, brief psychotic disorder, schizophreniform disorder) and 76 healthy controls....
- Letter to the Editor: THE IMPACT OF THE COVID-19 PANDEMIC ON SCHIZOPHRENIA PATIENTSby Emine Ilgın Hoşgelen on October 12, 2021
Dear Editor, The Covid-19 pandemic affected human life globally, inducing much stress on daily living (Çakıroğlu et al. 2020). Although assessments of general mental health during the Covid-19 pandemic have been widely reported, there is not adequate research on how schizophrenia patients have been affected. According to the World Health Organization (2020), individuals with chronic diseases who do not pay attention to their personal hygiene and the rules of protection from COVID-19 have a...
- Complete agenesis of the corpus callosum in paranoid schizophrenia-a case reportby Hari Neupane on October 11, 2021
Corpus callosum agenesis is a rare condition and is sometimes associated with schizophrenia. The co-existence of these two conditions adds value to the neurodevelopmental theory of schizophrenia.
- Homicides committed by delusional patients in the early 20th and 21st centuries: A study conducted in a French secure unitby Eloïse Provoost on October 11, 2021
Homicides committed by delusional patients are the object of a rich scientific literature, which puts the risk of such acts occurring into perspective when analyzing the offenders' sociodemographic and clinical characteristics. However, few articles detail the themes and mechanisms underlying those patients' delusions. To help bridge that gap, the authors conducted this retrospective descriptive study, including two samples of delusional homicidal patients, one from near present day and one from...