Delirium
Delirium is an abrupt change in the brain that causes mental confusion and emotional disruption. It makes it difficult to think, remember, sleep, pay attention, and more. You might experience delirium during alcohol withdrawal, after surgery, or with dementia.
Cluster Number:
Wiki Number: W052
Diagnosis: Delerium
US Patients: 1-2%, more with age
World Patients:
Sex Ratio:
Age Onset: most after 65
Brain Area: imbalance in dopamine and serotonin
Symptoms: confusion for hours or days, disorientation, disorganized thinking, uncontrolled muscles
Progression:
Causes: drug withdrawal, too much alcohol, prior dementia, sepsis-illness
Medications: haliperidol and other antipsychotics; 60% death rate in hospitalized elders with delerium, increases dementia X13.
Therapies: Maximize oxygen, hydration, feeding, pain control, control of other factors affecting the brain
YouTube Video: Understanding Delirium
Amazon or Library Book: Delirium
Delirium: Screening, Prevention, and Diagnosis – A Systematic Review of the Evidence
Click the book to link or order from Amazon.
Click the book to link or order from Amazon.
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Efficacy and safety of ciprofol for agitation and delirium in the ICU: A multicenter, single-blind, 3-arm parallel randomized controlled trial study protocolby Guo Liang Liu on January 26, 2023
BACKGROUND: Agitation is very common in the intensive care unit (ICU). The causes include pain, delirium, underlying disease, withdrawal syndrome, and some drug treatments. The practical goal of ICU treatment is to find an appropriate sedation regimen to reduce pain, restlessness, and delirium. Previous trials have examined the use of dexmedetomidine, but no trials have evaluated the efficacy and safety of ciprofol, a new sedative drug.
- Original Research: Patient-to-Nurse Violence During One-to-One Assignments: A Silent Epidemicby Miranda Squire on January 26, 2023
CONCLUSIONS: This study adds to the work of researchers who are asking difficult questions about workplace violence. It's our hope that the participants' comments and insights, as well as their recommendations, can move the needle in improving prevention and follow-up practices related to patient-initiated workplace violence.
- Relationship Among Clinically Obtained Biomarkers of Inflammation, Hypercoagulability, and Macrophage Activation, and Delirium in Critically Ill Patients With COVID-19by Sikandar H Khan on January 26, 2023
CONCLUSIONS: Our hypothesis-generating study found d-dimer and ferritin were associated with delirium/coma the following day, as well as delirium and coma independently. CRP was associated with next day coma and delirium severity. Larger studies to validate these results are needed.
- Association of preoperative prognostic nutritional index with risk of postoperative delirium: A systematic review and meta-analysisby Kuo-Chuan Hung on January 26, 2023
CONCLUSION: Our results demonstrated a negative association between PNI and POD, which warrant further large-scale studies for validation.