Conversion Disorder

Conversion disorder is a mental condition in which a person has blindness, paralysis, or other nervous system (neurologic) symptoms that cannot be explained by medical evaluation.


Cluster Number:
Wiki Number: W049
Diagnosis: Conversion Disorder
US Patients: 0.11-0.5%
World Patients:
Sex Ratio: 1M;4W
Age Onset: Ages-10-35
Brain Area: large epinephrine release
Symptoms: psychologically triggered neurological symptoms, numbness, blindness, paralysis or fits,etc.
Progression: Trauma suddenly converted by the brain into physical limitations.
Causes: serious difficulties when no physical basis can be found; usually in motor or sensory systems
Therapies: hypnosis, psychotherapy, physical therapy, stress management, transcranial magnetic stimulation; depression may occur.


The world-wide medical research
reports chosen for each diagnosis 

Clicking each title opens the
PubMed article’s summary-abstract.

  • Local-Disorder-Induced Low Thermal Conductivity in Degenerate Semiconductor Cu(22)Sn(10)S(32)
    by Ventrapati Pavan Kumar on October 13, 2021

    S-based semiconductors are attracting attention as environmentally friendly materials for energy-conversion applications because of their structural complexity and chemical flexibility. Here, we show that the delicate interplay between the chemical composition and cationic order/disorder allows one to stabilize a new sphalerite derivative phase of cubic symmetry in the Cu-Sn-S diagram: Cu(22)Sn(10)S(32). Interestingly, its crystal structure is characterized by a semiordered cationic...

  • Neurofilament light chain and α-synuclein RT-QuIC as differential diagnostic biomarkers in parkinsonisms and related syndromes
    by Corinne Quadalti on October 12, 2021

    Neurofilament light chain (NfL) and α-synuclein oligomeric seeds (α-syn-s) are promising biomarkers for patients with parkinsonism. We assessed their performance in discriminating Parkinson disease (PD) from atypical parkinsonisms (APDs) and evaluated the association between NfL levels and clinical measures of disease severity. We measured NfL in cerebrospinal fluid (CSF) and/or plasma by immunoassays and α-syn-s in CSF by real-time quaking-induced conversion (RT-QuIC) in patients with PD (n =...

  • Treatment With Nepicastat Decreases Contextual Traumatic Memories Persistence in Post-traumatic Stress Disorder
    by Raquel Martinho on October 11, 2021

    Post-traumatic stress disorder (PTSD) is a common anxiety mental disorder and can be manifested after exposure to a real or perceived life-threatening event. Increased noradrenaline and adrenaline in plasma and urine have been documented in PTSD. Dopamine-β-hydroxylase (DBH) catalyzes the conversion of dopamine to noradrenaline and consequently, DBH inhibition reduces catecholamines. Our aim was to evaluate if nepicastat treatment decreases PTSD signs in an animal model. Wild-type (129x1/SvJ)...

  • Hypnosis in the Treatment of Pediatric Functional Neurological Disorder: The Magic Glove Technique
    by Justin Coogle on October 8, 2021

    The treatment of functional neurological disorder (FND), previously referred to as conversion disorder, can be challenging. Despite these challenges and with increased understanding of this condition, new treatment options are emerging. One such treatment is hypnosis, which has a long history of use in the treatment of FND. Jean-Martin Charcot, considered by many to be the father of modern neurology, used therapeutic hypnosis as early as the 19^(th) century. In this report, we discuss the novel...