A circadian rhythm (/sərˈkeɪdiən/), or circadian cycle, is a natural, internal process that regulates the sleep–wake cycle and repeats roughly every 24 hours. It can refer to any process that originates within an organism (is endogenous) and responds to the environment (entrained by the environment).
Wiki Number: W042
Diagnosis: Circadian Rhythm Sleep Disorder
Brain Area: suprachiasmic nucleus
Symptoms: falling asleep in daytime; biological clock misaligned with circadian rhythm.
Causes: intrinsic: delayed, advanced, irregular or blindness; extrinsic: shift–work, jet-lag; Alzheimer’s often destroys patterns
Medications: None listed.
Therapies: chronotherapy-delay to normalize; light therapy; hypnotics; melotonin in evening; dark therapy
4 CURRENT ARTICLES
The world-wide medical research
reports chosen for each diagnosis
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PubMed article’s summary-abstract.
- Association of natural light exposure and delirium according to the presence or absence of windows in the intensive care unitby Hyo Jin Lee on October 26, 2021
CONCLUSIONS: Exposure to natural light through windows was associated with a lower incidence of delirium in the ICU.
- Diurnal Variation in SARS-CoV-2 PCR Test Results: Test Accuracy May Vary by Time of Dayby Candace D McNaughton on October 26, 2021
False negative tests for SARS-CoV-2 are common and have important public health and medical implications. We tested the hypothesis of diurnal variation in viral shedding by assessing the proportion of positive versus negative SARS-CoV-2 reverse transcription polymerase chain reaction (RT-PCR) tests and cycle time (Ct) values among positive samples by the time of day. Among 86,342 clinical tests performed among symptomatic and asymptomatic patients in a regional health care network in the...
- CRY1 Regulates Chemoresistance in Association With NANOG by Inhibiting Apoptosis via STAT3 Pathway in Patients With Cervical Cancerby Gwan Hee Han on October 26, 2021
CONCLUSION: CRY1 and NANOG over-expression serves as a strong predictive biomarker for prognosis and chemoradiation response, and may be a new therapeutic target in patients with cervical cancer.
- Aging effects on the diurnal patterns of gut microbial composition in male and female miceby Hyun-Jung Kim on October 26, 2021
Composition of the gut microbiota changes with aging and plays an important role in age-associated disease such as metabolic syndrome, cancer, and neurodegeneration. The gut microbiota composition oscillates through the day, and the disruption of their diurnal rhythm results in gut dysbiosis leading to metabolic and immune dysfunctions. It is well documented that circadian rhythm changes with age in several biological functions such as sleep, body temperature, and hormone secretion. However, it...