Circadian Rhythm
A circadian rhythm (/sərˈkeɪdiən/), or circadian cycle, is a natural, internal process that regulates the sleep–wake cycle and repeats roughly every 24 hours. It can refer to any process that originates within an organism (is endogenous) and responds to the environment (entrained by the environment).
Cluster Number:
Wiki Number: W042
Diagnosis: Circadian Rhythm Sleep Disorder
US Patients:
World Patients:
Sex Ratio:
Age Onset:
Brain Area: suprachiasmic nucleus
Symptoms: falling asleep in daytime; biological clock misaligned with circadian rhythm.
Progression:
Causes: intrinsic: delayed, advanced, irregular or blindness; extrinsic: shift–work, jet-lag; Alzheimer’s often destroys patterns
Medications: None listed.
Therapies: chronotherapy-delay to normalize; light therapy; hypnotics; melotonin in evening; dark therapy
Youtube Video: Circadian Rhythm Disorders
Amazon or Library Book: Sleep . . . Natural Remedies
Amazon or Library Book:
How to Sleep Well
Click the book to link or order from Amazon.
Click the book to link or order from Amazon.
Support Group: circadiansleepdisorders.org; Email-csd-n@cst-n.org (Circadian Sleep Disorders Network)
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- The use of prolonged-release melatonin in circadian medicine: a systematic reviewby Antonio Del Casale on May 7, 2024
CONCLUSIONS: Overall, PRM in circadian medicine is an effective chronopharmaceutical for restoring the sleep-wake rhythm in patients with insomnia disorder. This efficacy may also extend to sleep disorders associated with mood, neurodevelopmental and neurocognitive disorders, suggesting a further potential role in insomnia associated with various organic diseases.
- The Association between Circadian Syndrome and Frailty in US adults: a cross-sectional study of NHANES Data from 2007 to 2018by Lirong Sun on May 7, 2024
CONCLUSION: This study identifies a strong positive correlation between CircS and frailty in the elderly. The risk of frailty escalates with an increasing number of CircS components. These findings highlight the intricate interplay between circadian syndrome and frailty in older adults, offering valuable insights for developing targeted prevention and intervention strategies.
- Association of Rest-Activity Rhythm and Risk of Developing Dementia or Mild Cognitive Impairment in the Middle-Aged and Older Population: Prospective Cohort Studyby Shahab Haghayegh on May 7, 2024
CONCLUSIONS: Based on findings from a large sample of middle-to-older adults with objective RAR assessment and almost 8-years of follow-up, we suggest that suppressed and fragmented daily activity rhythms precede the onset of dementia or MCI and may serve as risk biomarkers for preclinical dementia in middle-aged and older adults.
- Commentary: Aripiprazole disrupts cellular synchrony in the suprachiasmatic nucleus and enhances entrainment to environmental light-dark cycles in miceby Tsuyoshi Kitajima on May 6, 2024
No abstract