Circadian Rhythm
A circadian rhythm (/sərˈkeɪdiən/), or circadian cycle, is a natural, internal process that regulates the sleep–wake cycle and repeats roughly every 24 hours. It can refer to any process that originates within an organism (is endogenous) and responds to the environment (entrained by the environment).
Cluster Number:
Wiki Number: W042
Diagnosis: Circadian Rhythm Sleep Disorder
US Patients:
World Patients:
Sex Ratio:
Age Onset:
Brain Area: suprachiasmic nucleus
Symptoms: falling asleep in daytime; biological clock misaligned with circadian rhythm.
Progression:
Causes: intrinsic: delayed, advanced, irregular or blindness; extrinsic: shift–work, jet-lag; Alzheimer’s often destroys patterns
Medications: None listed.
Therapies: chronotherapy-delay to normalize; light therapy; hypnotics; melotonin in evening; dark therapy
Youtube Video: Circadian Rhythm Disorders
Amazon or Library Book: Sleep . . . Natural Remedies
Amazon or Library Book:
How to Sleep Well
Click the book to link or order from Amazon.
Click the book to link or order from Amazon.
Support Group: circadiansleepdisorders.org; Email-csd-n@cst-n.org (Circadian Sleep Disorders Network)
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- The Association Between Delayed Sleep-Wake Phase Disorder and Depression Among Young Individuals: A Systematic Review and Meta-Analysis: Association entre le syndrome de retard de phase et la dépression parmi les jeunes : revue systématique et méta-analyseby Manish H Dama on March 25, 2025
ObjectivesDelayed sleep-wake phase disorder (DSWPD) most commonly affects young individuals (adolescents and young adults), but it is often undetected in clinical practice. Despite several reports suggesting a link between DSWPD and depression, no systematic review has investigated this association. The aim of this systematic review was to determine whether DSWPD is associated with depression among young individuals.MethodsMEDLINE, EMBASE, PsycINFO, and CINAHL Plus were searched up to 29 July...
- Light physical activity throughout the day and physical function in older adults: A cross-sectional studyby Ting-Fu Lai on March 25, 2025
Research has demonstrated that habitual light physical activity (LPA) in later life may contribute to preventing muscle loss and disability in older adults. Given that LPA dominated overall physical activity duration throughout the day, investigating the impact of the timing of LPA on physical function among older adults is essential for optimizing health interventions. This cross-sectional study explored the association between LPA timing and performances in four physical function tests among...
- Rest-Activity Disturbances Correlate with Core Features in Dementia with Lewy Bodiesby Jack Anderson on March 25, 2025
CONCLUSIONS: Actigraphy detects distinct rest-activity rhythm disruptions in DLB, differentiating it from PD and controls. These measures are associated with the severity of core clinical features in DLB.
- Correlation between levels of clock protein expression and effects on temozolomide-resistant glioblastoma and tumor progressionby Keng-Liang Kuo on March 24, 2025
Glioblastoma (GBM) is the most common malignant intracranial neoplasm. Treatment with surgical resection and concurrent chemoradiotherapy may not achieve satisfactory results in life expectancy. Temozolomide (TMZ) chemoresistance is one of the most common reasons for treatment failure, but the role of the circadian cycle and autophagic pathways in this phenomenon is unknown. This study investigated the relationship between the circadian cycle and autophagic pathways in GBM and its TMZ...