Catalepsy (from Ancient Greek katálēpsis, κατάληψις, “seizing, grasping”) is a nervous condition characterized by muscular rigidity and fixity of posture regardless of external stimuli, as well as decreased sensitivity to pain.
Wiki Number: W035
Symptoms: muscular rigidy and increased pain; slowing of bodily functions, such as breathing
Progression: Shakespeare used it in “Romeo and Juliet.” Other authors have described people thought to be dead instead.
Causes: varies: cocaine withdrawal, reaction to drugs to treat schizophrenia
Medications: None described.
Therapies: None described.
4 CURRENT ARTICLES
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- The effects of galangin in prepulse inhibition test and experimental schizophrenia modelsby Bilgin Kaygisiz on October 20, 2021
CONCLUSION: We suggest that galangin may help enhance schizophrenia-associated cognitive deficits, and nicotinic, muscarinic cholinergic and serotonin-1A receptors are not involved in this effect. Galangin also exerted an antipsychotic-like effect without inducing catalepsy and may be considered as an advantageous antipsychotic agent.
- The potential neuroprotective effect of diosmin in rotenone-induced model of Parkinson's disease in ratsby Christine N Habib on October 17, 2021
Most treatments for Parkinson's disease (PD) focus on improving the symptoms and the dopaminergic effects; nevertheless, they cannot delay the disease progression. Diosmin (DM), a naturally occurring flavone that is obtained from citrus fruits, has demonstrated anti-apoptotic, anti-inflammatory and antioxidative properties in many diseases. This study aimed to assess the neuroprotective effects of diosmin in rotenone-induced rat model of PD and investigate its potential underlying mechanisms. A...
- Cannabinoid tetrad effects of oral Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) in male and female rats: sex, dose-effects and time course evaluationsby Catherine F Moore on October 15, 2021
CONCLUSIONS: Oral THC and CBD produced long lasting effects that differed in magnitude and time course when compared with other routes of administration. Examination of cannabinoid effects administered via different routes of administration, species, and in both males and females is critical to enhance translation.
- Garcinol blocks motor behavioural deficits by providing dopaminergic neuroprotection in MPTP mouse model of Parkinson's disease: involvement of anti-inflammatory responseby Banashree Chetia Phukan on October 11, 2021
Although the etiology of Parkinson's disease (PD) is poorly understood, studies in animal models revealed loss of dopamine and the dopaminergic neurons harbouring the neurotransmitter to be the principal cause behind this neuro-motor disorder. Neuroinflammation with glial cell activation is suggested to play a significant role in dopaminergic neurodegeneration. Several biomolecules have been reported to confer dopaminergic neuroprotection in different animal models of PD, owing to their...