Caffeine Withdrawal
Caffeine withdrawal can occur in anyone who regularly consumes caffeine and then abruptly discontinues its use. Common symptoms include headache, fatigue, low energy, irritability, anxiety, poor concentration, depressed mood and tremors, which can last anywhere from two to nine days.
Cluster Number:
Wiki Number:
Diagnosis: W032
US Patients: Caffeine (Withdrawal)
World Patients: 84% daily
Sex Ratio:
Age Onset:
Brain Area:
Symptoms: interrupts adenosine’s natural tiredness inside of the blood-brain barrier, stimulates dopamine
Progression: reduces fatigue and drowsiness; improves reaction time, concentration and motor coordination.
Causes: primary benefit 1 hour – 3-4 hours after drinking; limit 2 cups during pregnancy; 3 cups during breast-feeding
Medications: withdrawal may induce sleepiness, irritability, headache and fatigue
Therapies: reducing caffeine decreases anxiety, jitters, anxiety attacks, depression and suicide
Amazon or Library Book: Caffeine Blues
Click the book to link or order from Amazon.
Support Group: SAMHSA; 800-662-4647;
(U.S. Government, Substance Abuse &
Mental Health Services Administration)
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Nutritional Intake and Timing of Marathon Runners: Influence of Athlete's Characteristics and Fueling Practices on Finishing Timeby Rubén Jiménez-Alfageme on March 16, 2025
CONCLUSIONS: The intake of CHO (35 ± 17 g/h), sodium (192 ± 150 mg/h) and caffeine (57 ± 49 mg/h) was low compared to the current recommendations during the competition. The intake of fluids (466 ± 279 mL/h) was at the lower limit of recommendations. Most athletes did not receive nutritional counselling by a sport dietitian, which may explain why athletes failed to meet specific nutrient recommendations. Future investigations with a larger sample size are warranted to assess the relationship...
- Habitual Caffeine Consumption and Training Status Affect the Ergogenicity of Acute Caffeine Intake on Exercise Performanceby Davar Khodadadi on February 5, 2025
CONCLUSION: Habituation to caffeine and training status could partially influence the ergogenic effects of caffeine on exercise performance.
- Network analysis of caffeine use disorder, withdrawal symptoms, and psychiatric symptomsby Mohammadreza Davoudi on January 21, 2025
CONCLUSIONS: Mental health providers should target these specific symptoms in clinical interventions to mitigate caffeine-related problems among individuals in the general population effectively.
- Withdrawal Syndromesby Mohit Gupta on January 1, 2025
Substance withdrawal is a common medical problem and is widely prevalent in many countries. Each withdrawal syndrome has 2 primary characteristics: a compensatory physiologic adaptation, which is intrinsic to the continuous exposure of the body to a drug or substance, and when decreasing amounts of the substance are available, the withdrawal develops. In addition, substances that produce withdrawal can be treated with the same or similar drug to relieve and treat the symptoms.