Caffeine Dependence
Caffeine is a commonplace central nervous system stimulant drug which occurs in nature as part of the coffee, tea, yerba mate, cocoa and other plants. It is also an additive in many consumer products, most notably beverages advertised as energy drinks and colas.
Cluster Number:
Wiki Number: W031
Diagnosis: Caffeine Dependence
US Patients:
World Patients:
Sex Ratio:
Age Onset:
Brain Area: Use increases dopamine and norepinephrine
Symptoms: Stimulates reward system, but not enough to hijack it like cocaine.
Progression: Stimulating adnosine receptors induces tiredness & need to sleep;
Causes: Effects of coffee lessen and tolerance increases because the body makes more adenosine receptors.
Medications: None listed.
Therapies: Reduction in coffee to decaffinated coffee or teas. Reduce children’s soft-drink consumption.
Youtube Video: History of Coffee-Global Addiction
Amazon or Library Book: Caffeine Addiction Cure:
The Ultimate Guide to Overcome Caffeine Addiction
Click the book to link or order from Amazon.
Support Group: caffeineaddictsanonymous.com; ON-line;
(12-Step Program)
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Modifiable risk factors associated with the risk of developing Parkinson's disease: a critical reviewby Vitor Tumas on March 19, 2025
The etiology of Parkinson's disease (PD) is complex and multifactorial, depending on interactions involving environmental/lifestyle and genetic factors. The genetic aspects of the disease are becoming well characterized, while the environmental factors still need further investigation. In the present narrative review, we have described the most concrete evidence of associations between environmental factors and the risk of developing PD. Physical activity, healthy dietary patterns, smoking, and...
- The role of molecular weight on chitosan and chitosan oligosaccharides in sleep regulation: Integrating network pharmacology and multi-omics analysis in Drosophilaby Yuxuan Liang on March 18, 2025
This study aims to investigate the sleep-regulating effects of chitosan (COS) with different molecular weights (1 kDa, 3 kDa and 30 kDa). Network pharmacology predicted the sleep-regulating effects of COS and COS oligosaccharides and identified sleep-related targets. Drosophila sleep analysis demonstrated that COS ameliorated caffeine-induced insomnia, and its efficacy was critically influenced by molecular weight. Specifically, COS30K exhibited superior effects compared to COS1K and COS3K in...
- A potentially lethal interaction: Migraine, human immunodeficiency virus and ergotism - A primary care case reportby Ismail Ahmad Sahli Mahzuz on March 17, 2025
Ergotism is a rare but potentially serious condition characterised by peripheral vasospasm. Its diagnosis is challenging because the presentation varies depending on the type and location of the affected blood vessels. Ergot alkaloids, including ergotamine, are metabolised by the cytochrome P450 isoenzyme CYP3A4. Concurrent use of ergotamine with CYP3A4 inhibitors can significantly increase the risk of ergotism. However, this potentially dangerous drug interaction is often underestimated in...
- Greater fatigue, disturbed sleep, persistent memory problems, and reduced CD4(+) T cell and B cell percentages in adults with a history of methamphetamine dependenceby Elizabeth K Wood on March 15, 2025
Methamphetamine (MA) dependence is associated with immunotoxicity and high rates of neuropsychiatric impairments that persist into remission. Although there are currently no FDA-approved pharmacotherapies for MA use disorders, preclinical and clinical studies are beginning to test interventions that directly impact immune signaling. This study was conducted to investigate the relative contribution of immune cell function to the neuropsychiatric sequelae associated with MA dependence and...