Autism Spectrum Disorder
Wiki Number: W017
Diagnosis: Autism Spectrum Disorder
US Patients: 1.5Mil
World Patients: 62Mil
Sex Ratio: 4B;1G
Age Onset: By 1
Brain Area: Enlarged frontal and temporal lobes, mirrror neurons, corpus callosum
Symptoms: poor communication, repetitive behaviors
Progression: delayed language & cognitive development; 50% head banging, self-biting;10% savants
Causes: 75% genetic from 1000 genes; not enough GABA, less brain connectivity between regions
Therapies: earlier, the better; teach coping skills, awareness of others’ presence, interests
4 CURRENT ARTICLES
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PubMed article’s summary-abstract.
- Pre-symptomatic intervention for autism spectrum disorder (ASD): defining a research agendaby Rebecca Grzadzinski on October 16, 2021
Autism spectrum disorder (ASD) impacts an individual's ability to socialize, communicate, and interact with, and adapt to, the environment. Over the last two decades, research has focused on early identification of ASD with significant progress being made in understanding the early behavioral and biological markers that precede a diagnosis, providing a catalyst for pre-symptomatic identification and intervention. Evidence from preclinical trials suggest that intervention prior to the onset of...
- Correlates of obesity in adolescents with and without autism spectrum disorder: The 2017-2018 National Survey of Children's Healthby Acadia W Buro on October 16, 2021
CONCLUSIONS: The association between obesity and ASD in this study highlights the need for greater attention to nutrition, physical activity, and co-occurring conditions among adolescents with ASD. Effective interventions to curtail the risks among racial/ethnic minority adolescents and adolescents with lower household income are needed. Further research is needed to examine additional factors associated with obesity in adolescents with ASD, including family, community, organizational, and...
- A Pilot Study of Self-Regulation and Behavior Problems in Preschoolers with ASD: Parent Broader Autism Phenotype Traits Relate to Child Emotion Regulation and Inhibitory Controlby Elizabeth A DeLucia on October 16, 2021
Little is known about the development of self-regulation processes during the preschool period in autism spectrum disorder (ASD). How parental characteristics such as the broader autism phenotype (BAP) relate to children's self-regulation is not well understood. Preschool-aged children with (n = 24) and without ASD (n = 21) completed an inhibitory control task and mothers reported on child emotion regulation and their own BAP traits. Children with ASD had lower emotion regulation, and emotion...
- Quality of life in adults with autism spectrum disorder: influence of age, sex, and a controlled, randomized mindfulness-based stress reduction pilot interventionby B Blair Braden on October 16, 2021
CONCLUSION: Findings encourage precision medicine approaches tailored to age and sex groups for best HRQoL outcomes in adults with ASD. ClinicalTrials.gov Identifier: NCT04017793.