Pain Med Case Rep. 2025 Oct;9(6):289-294.

ABSTRACT

BACKGROUND: In this peculiar case study, we extensively explored the effects of 6 weeks of supervised yoga on the endogenous pain modulatory system, autonomic profile, and corticomotor excitability.

CASE REPORT: A 29-year-old woman diagnosed with fibromyalgia (FMS) was suggested 6 weeks of supervised yoga because the pharmaceutical treatments were ineffective. Assessment was done at baseline, 2 weeks, and post-6 weeks for pain, cognitive skills, sleep quality, anxiety, and depression status. An autonomic profile was done, followed by flexibility and corticomotor excitability assessments.

CONCLUSIONS: Reduction in pain and tender points. Improvements in sleep quality, flexibility, and cognitive skills were observed after 6 weeks. Pain perception and cortical plasticity showed improvement. Autonomic function test shows higher high frequency after intervention. This report supports the view that yoga, as a holistic approach alone, is effective in ameliorating pain and improving dysautonomia. Hence, it may be considered as a therapeutic intervention for FMS in rare cases.

PMID:41135018