Sleep Med. 2025 Aug 7;134:106735. doi: 10.1016/j.sleep.2025.106735. Online ahead of print.
ABSTRACT
BACKGROUND: Hypersomnia disorders are complex both diagnostically and management wise. Complex medical conditions benefit from multidisciplinary board (MDB). We describe the structure, implementation, and preliminary outcomes of a hypersomnia MDB established to improve diagnosis and management of complex hypersomnia cases.
METHODS: We implemented a monthly virtual case-based conference at a large VA medical center, involving clinicians from sleep medicine, psychiatry, neurology, clinical psychology, and pharmacy. Patients with central hypersomnia disorders, diagnostic uncertainty, or management challenges were selected for discussion. Presenting providers summarized patient histories, diagnostics, and treatment concerns. A multidisciplinary group reviewed each case, and consensus recommendations were documented in the electronic health record.
RESULTS: Over two years, 33 unique patients were presented. Final diagnoses included narcolepsy type 1 (9/33), narcolepsy type 2 (9/33), idiopathic hypersomnia (6/33), and primary obstructive sleep apnea (6/33). Comorbid mental illness (e.g., depression in 15/33, post-traumatic stress disorder or PTSD in 9/33) and obstructive sleep apnea (18/33) were common. The board recommended medication changes in 8/33 patients, mental health referrals in 5/33, and further diagnostic testing in 8/33. Clinician feedback indicated improved diagnostic clarity, enhanced collaboration, and educational benefit, especially for sleep medicine trainees.
CONCLUSIONS: Establishing a hypersomnia MDB is feasible and promotes collaborative care, improves diagnostic accuracy and treatment plans for patients with complex hypersomnia, and enhances trainee education. Future directions include measuring treatment outcomes, assessing care barriers, tracking clinical responses over time, and expanding to larger scale operations.
PMID:40818167 | DOI:10.1016/j.sleep.2025.106735
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