Effects of cognitive combined with mindfulness-based stress reduction and sleep in patients with diabetes and endometrial cancer

World J Psychiatry. 2025 Apr 19;15(4):100849. doi: 10.5498/wjp.v15.i4.100849. eCollection 2025 Apr 19.

ABSTRACT

BACKGROUND: Seek highly effective treatment measures for improving mood and sleep.

AIM: To explore the effects of mood and depression in patients with endometrial cancer after cognitive behavioral therapy (CBT) and mindfulness-based stress reduction.

METHODS: In a prospective study, 90 patients with diabetes, endometrial cancer, and depression were selected from January 2023 to January 2024 in our hospital. There were 45 patients in the control group and 45 patients in the observation group. In addition to the conventional treatment, the control group received cognitive behavioral treatment, and the observation group: Control group was given to compare changes in mood state and sleep quality before and after the intervention. Follow-up was performed3 months after treatment completion.

RESULTS: Before treatment, the mood and sleep quality scores between the two groups (P > 0.05); in the observation group, the 5 negative mood scores were lower and lower than the control group; the 2 positive mood scores were higher than in the control group, and the difference was statistically significant (P < 0.05); compared with before treatment, the 7 sleep quality scores and Pittsburgh sleep quality index scale total score in the observation group and lower in the control group (P < 0.05).

CONCLUSION: In patients with diabetes and endometrial cancer, mood state and sleep quality significantly improved after CBT and breathing relaxation. These findings provide new and effective treatment strategies in clinical practice.

PMID:40309606 | PMC:PMC12038674 | DOI:10.5498/wjp.v15.i4.100849