BACKGROUND: Amphetamine-type stimulant (ATS) abuse is strongly associated with an elevated risk of HIV infection and transmission. Antiretroviral therapy (ART) serves as the primary approach for managing HIV infection and AIDS progression. However, ATS abuse diminishes the efficacy of ART in HIV/AIDS patients, amplifying the vulnerability to immunological non-response (INR) and ultimately increasing the incidence rate and mortality of opportunistic infections. Currently, no effective...

Acute high-intensity interval training (HIIT) has cognitive benefits in individuals with methamphetamine use disorder (MUD), yet it remains largely unknown the benefits of long-term HIIT on emotional conflict control and its neural mechanism in individuals with MUD. The current study conducted a 36-week low-volume HIIT intervention to investigate the effects of HIIT on emotional conflict control in males with MUD and their prefrontal cortex (PFC) activation. This study was a sub-study of the...

CONCLUSIONS: Treatment completion was moderated by a range of factors including drug type, treatment modality and duration, and referral source. Low rates of amphetamine treatment completion across treatment modalities confirms the urgent need for further research investigating more effective treatment options for amphetamine use disorders.

CONCLUSIONS: Myocardial dissection with aneurysm formation is a rare complication of ischaemic heart disease. Methamphetamines enhance the risk of myocardial dissection by inducing myocardial inflammation, causing a dilated cardiomyopathy and increasing the left ventricular pressures.