Background/Objectives: Regadenoson, a selective adenosine A(2A) receptor agonist, is primarily prescribed for myocardial perfusion imaging (MPI). As its clinical use becomes more widespread in practice, assessing its safety in real-world settings is essential. Methods: In this research, disproportionality analysis was applied to evaluate the safety of Regadenoson by examining all adverse event (AE) reports since 2004 in the FDA Adverse Event Reporting System (FAERS), in which Regadenoson was...

CONCLUSIONS: These findings showed changes in the principal MS network gradient in SCZ and offered potential molecular explanations for the structural changes underpinning SCZ.

Two-dimensional (2D) hybrid organic-inorganic perovskites exhibit pronounced Rashba splitting, positioning them as promising candidates for spintronic applications. However, the underlying mechanism of inversion symmetry breaking and its impact on excitonic optical properties remains elusive. In this study, we investigate a series of 2D Ruddlesden-Popper perovskites and reveal that the order-disorder transition induced by phenyl-based cations triggers a dynamic Rashba effect. At the critical...

Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder worldwide, causing dementia and affecting millions of individuals. One prominent characteristic in the brains of AD patients is glucose hypometabolism. In the context of galactose metabolism, intracellular glucose levels are heightened. Galactose mutarotase (GALM) plays a crucial role in maintaining normal galactose metabolism by catalyzing the conversion of β-D-galactose into α-D-galactose (α-D-G). The latter is then...