Substance-Related Disorder
A chronic disease characterized by uncontrolled drinking and preoccupation Excessive use of psychoactive drugs, such as alcohol, pain medications, or illegal drugs. It can lead to physical, social, or emotional harm.
Cluster Number:
Wiki Number: PW215
Diagnosis: Substance-Related Disorder
US Patients: 7% of adults; 5% for alcohol; 2% for other drugs; 72,000 deaths from drug overdoses in 2017; 88,000 alcohol&480,000 tobacco deaths
World Patients: 2017-271 million (5.5% of adults) have used illicit drugs and 35 million, have an use disorder; 585,000 drug-deaths
Sex Ratio: Alcohol-only disorder 237 million men and 46 million women; 3 million alcohol-related deaths.
Age Onset: Children have 2X substance use disorders if parents hae them vs. parents without them.
Brain Area:
Symptoms: persistent use despite harm and adverse consequences: alcohol, caffeine, pot, phencyclidine, hallucinogens, inhalants, opioids, etc
Progression: can be mild, moderate or severe damage
Causes:
Medications: detox; FDA has 2 for alcohol and opioid use; none for the cocaine, methamphetamine or other substance use disorders
Therapies:
Youtube Video: Substance Use Disorders-Dopamine Pathway
Youtube Video:
Substance Abuse Disorders
Amazon or Library Book:
Stahl’s Illustrated Substance Use and Impulsive Disorders
Support Group: Samhsa.gov; 800-662-4357
(U.S. Government Helpline)
Contact your local Social Security office for possible Disability Benefits through their Disability Determination Services,
Section 12.02.
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosisÂ
Clicking each title opens the
PubMed article’s summary-abstract.
- Can Fentanyl Test Strips Modify How People Use Drugs?by Vania Modesto-Lowe on May 19, 2024
No abstract
- The role of metabolic syndrome as a mediator in the relationship between CCL11 levels and the presence of a mood episode with mixed features in young adults with bipolar disorderby LetĂcia Vasques Bender on May 18, 2024
Mixed features presentation in bipolar disorder (BD) represents the most severe form of the disease. BD may lead to cognitive and functional deterioration, a process known as neuroprogression, which appears to be exacerbated by increased serum levels of CCL11, a neuroprogression-related cytokine. Metabolic syndrome (MetS) is highly prevalent in BD, and it is known that the presence of MetS may increase inflammation, which may contribute to increased CCL11 levels, and consequently impact on the...
- Patient navigation for perinatal substance use disorder treatment: A systematic reviewby Kathryn Wouk on May 18, 2024
CONCLUSION: Patient navigation may be a promising strategy for improving maternal and infant health outcomes among perinatal persons who use substances. More experimental research is needed to test the effect of patient navigation programs for perinatal persons who use substances compared to other models of care.
- Exploring peripheral biomarkers in psychostimulant use: a systematic review on neurotrophins, stress-related hormones, oxidative stress molecules and genetic factorsby Mancusi Gianluca on May 18, 2024
CONCLUSIONS: Neurotrophins and inflammatory molecules play a significant role in the pathophysiological mechanisms following psychostimulant use. A better understanding of their complex interplay could aid clinicians in identifying biomarkers of different disease stages. Moreover, clinical interventions designed to interfere with neurotrophic and inflammatory pathways could possibly lead to craving-modulatory strategies and reduce pathological neuronal and systemic consequences of...