Alcoholism
A chronic disease characterized by uncontrolled drinking and preoccupation with alcohol.
Alcoholism is the inability to control drinking due to both a physical and emotional dependence on alcohol.
Symptoms include a strong need or urge to use alcohol. Those with alcohol use disorder may have problems controlling their drinking, continue to use alcohol even when it causes problems, or have withdrawal symptoms when they rapidly decrease or stop drinking.
Treatment involves counseling, such as behavioral therapy, and medications that reduce the desire to drink. Some people need medical detoxification to stop drinking safely. Mutual support groups help people stop drinking, manage relapses and cope with necessary lifestyle changes.
Cluster Number:
Wiki Number: W0004
Diagnosis: Alcoholism
US Patients: 2016-5.1%
World Patients: 380Million
Sex Ratio: 2M-1F
Age Onset:
Brain Area:
Symptoms: Overstimulation of GABA receptors
Progression: increasing drinking
Causes: Cirrhosis of the liver, epilesy, cancer; dementia, women more likely
Medications: Acamprosate, naltrexone, opoids,
Therapies: Alcoholics Anonymous and 12-Step programs
Youtube Video: Warning Symptoms of Alcoholism
Amazon or Library Book:
Understanding Alcoholism as a Brain Disease
Click the book to link or order from Amazon.
Support Group: Alcoholics Anonymous-aa.org
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Novel therapeutics to treat chronic pancreatitis: targeting pancreatic stellate cells and macrophagesby Srikanth Iyer on May 18, 2024
INTRODUCTION: Chronic pancreatitis (CP) is a persistent, recurrent, and progressive disorder that is characterized by chronic inflammation and irreversible fibrosis of the pancreas. It is associated with severe morbidity, resulting in intense abdominal pain, diabetes, exocrine and endocrine dysfunction, and an increased risk of pancreatic cancer. The etiological factors are diverse and the major risk factors include smoking, chronic alcoholism, as well as other environmental and genetic factors....
- Nitrogen-doped magnetic porous carbon nanospheres derived from dual templates-induced mesoporous polydopamine coated Fe3O4 for efficient extraction and sensitive determination of volatile nitrosamines by gas chromatography-mass spectroscopyby Kai Yang on May 18, 2024
N-nitrosamines (NAs) are highly carcinogenic compounds commonly found in food, beverages, and consumer products. Due to their wide polarity range, it is challenging to find a suitable carbon adsorbent that can simultaneously adsorb and enrich both polar and nonpolar NAs with good recovery. In this study, nitrogen-doped magnetic mesoporous carbon nanospheres (M-MCN) were prepared and employed as an adsorbent for magnetic solid-phase extraction (MSPE) to extract and concentrate four NAs. The...
- Integrating the Patient's Voice into the Research Agenda for Treatment of Chemosensory Disordersby Claire Murphy on May 18, 2024
World-wide some 658 million people were infected with COVID-19 and millions suffer from chemosensory impairment associated with long COVID. Current treatments for taste and smell disorders are limited. Involving patients has the potential to catalyze the dynamic exchange and development of new ideas and approaches to facilitate biomedical research and therapeutics. We assessed patients' perceptions of the efficacy of treatments for chemosensory impairment using an online questionnaire completed...
- Myeloid AMPK signaling restricts fibrosis but is not required for metformin improvements during CDAHFD-induced NASH in miceby Julia R C Nunes on May 18, 2024
Metabolic programming underpins inflammatory processes of immune cells. In the context of chronic liver disease, liver macrophage activation and response to hepatocellular damage is dependent on profound metabolic changes. Here, we sought to identify the role of an important metabolic regulator, AMP-activated protein kinase (AMPK), specifically within myeloid cells during the progression of non-alcoholic steatohepatitis (NASH) and whether treatment with metformin, a first line therapy for...