Frontotemporal Cognitive Disorder
Resources for Patients and Caregivers
Frontotemporal disorders (FTD), sometimes called frontotemporal dementia, are the result of damage to neurons in the frontal and temporal lobes of the brain. Many possible symptoms can result, including unusual behaviors, emotional problems, trouble communicating, difficulty with work, or difficulty with walking.
Cluster Number:
Wiki Number: 19-Frontotemporal Cognitive Disorder
Diagnosis:
US Patients:
World Patients:
Sex Ratio:
Age Onset:
Brain Area: frontal lobe
Symptoms: difficulties with cognitive (movement and speech), emotional or behavioral activities
Progression:
Causes: brain injuries, frontotemporal-dementia or Alzheimer’s diseases
Medications:
Therapies: speech therapy
Youtube Video: 60 Minutes Archive: Frontotemporal Dementia
Amazon or Library Book: Frontotemporal Related Dementias
Click the book to link or order from Amazon.
Support Group: info@theaftd.com; 866-507-7222
(Association for Frontotemporal Degeneration)
Resources for Physicians, Counselors and Researchers
4 CURRENT ARTICLES
FROM PUBMED
The world-wide medical research
reports chosen for each diagnosis
Clicking each title opens the
PubMed article’s summary-abstract.
- Cerebrospinal fluid/serum albumin ratio in patients with Lewy body disease: a systematic review and meta-analysisby Moyu Li on May 17, 2024
CONCLUSION: Qalb levels were significantly elevated in LBD patients compared with normal older adults and were higher than those in AD patients and FTLD patients, which helped in the differential diagnosis of LBD from other neurodegenerative diseases.
- Symptomatic progression of frontotemporal dementia with the TARDBP I383V variantby Peter S Pressman on May 17, 2024
We present a longitudinal description of a man with the TARDBP I383V variant of frontotemporal dementia (FTD). His progressive changes in behavior and language resulted in a diagnosis of the right temporal variant of FTD, also called the semantic behavioral variant (sbvFTD). We also present data from a small series of patients with the TARDBP I383V variant who were enrolled in a nationwide FTD research collaboration (ALLFTD). These data support slowly progressive loss of semantic function. While...
- Profiles of motivational impairment and their relationship to functional decline in frontotemporal dementiaby Siobhán R Shaw on May 17, 2024
Motivational disturbances are pervasive in frontotemporal dementia (FTD) and impact negatively on everyday functioning. Despite mounting evidence of anhedonia in FTD, it remains unclear how such changes fit within the broader motivational symptom profile of FTD, or how anhedonia relates to functional outcomes. Here we sought to comprehensively characterize motivational disturbances in FTD and their respective relationships with functional impairment. A cross-sectional study design was used...
- Tau filaments with the chronic traumatic encephalopathy fold in a case of vacuolar tauopathy with VCP mutation D395Gby Chao Qi on May 17, 2024
Dominantly inherited mutation D395G in the gene encoding valosin-containing protein causes vacuolar tauopathy, a type of behavioural-variant frontotemporal dementia, with marked vacuolation and abundant filamentous tau inclusions made of all six brain isoforms. Here we report that tau inclusions were concentrated in layers II/III of the frontotemporal cortex in a case of vacuolar tauopathy. By electron cryomicroscopy, tau filaments had the chronic traumatic encephalopathy (CTE) fold. Tau...