Recurrent brief depression
Recurrent brief depression (RBD) defines a mental disorder characterized by intermittent depressive episodes, not related to menstrual cycles in women, occurring between approximately 6–12 times per year, over at least one year or more fulfilling the diagnostic criteria for major depressive episodes (DSM-IV and ICD-10) except for duration which in RBD is less than 14 days, typically 5–7 days.
Wiki Number: PW183
Diagnosis: Recurrent Brief Depression
World Patients: 2.6-10% (Unfortuately, whether these were percentages of depression sufferers or of the general population was not clarified.)
Brain Area: temporal lobe epilepsy for a small portion.
Symptoms: Typically 5-7 days, 6-12 X per year, (not linked with menstrual periods) with impared function and ideas of suicide. Poor sleep;
Progression: may include “somatic syndrome” pain, poor sleep, muscular weakness, etc.; or psychotic symptoms
Causes: genetic factors; may relate to bipolar disorders.
Medications: lithium, SSRIs, mood stabilizers
Therapies: None listed.
4 CURRENT ARTICLES
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PubMed article’s summary-abstract.
- Comparison of Residual Depressive Symptoms, Functioning, and Quality of Life Between Patients with Recurrent Depression and First Episode Depression After Acute Treatment in Chinaby Si Zu on October 11, 2021
CONCLUSION: The recurrent patients have more severe social function impairment, depressive symptoms, and lower life quality than that of the first-episode depressed patients. Given the negative impact of depressed symptom on recurrent patient, more attention should be paid to the treatment of recurrent patient and recurrence prevention of first episode patient.
- Psychobiology of Stress and Adolescent Depression (PSY SAD) Study: Protocol overview for an fMRI-based multi-method investigationby Stassja Sichko on October 1, 2021
Depression is a common, often recurrent disorder that causes substantial disease burden worldwide, and this is especially true for women following the pubertal transition. According to the Social Signal Transduction Theory of Depression, stressors involving social stress and rejection, which frequently precipitate major depressive episodes, induce depressive symptoms in vulnerable individuals in part by altering the activity and connectivity of stress-related neural pathways, and by upregulating...
- Intravenous Ketamine Infusions in Treatment-Resistant Bipolar Depression: An Open-Label Naturalistic Observational Studyby Alina Wilkowska on August 23, 2021
CONCLUSION: This report presents the preliminary results of IV ketamine effectiveness and safety in treatment-resistant bipolar depression. The findings suggest that it is a feasible, safe and well-tolerated treatment option in this group of patients. There is a definite need for more studies in this field.
- Threat-Modulation of Executive Functions-A Novel Biomarker of Depression?by Jari Peräkylä on July 19, 2021
Background: Alterations in executive functions, emotion regulation, and their interaction are common concomitants of depression. Executive dysfunction frequently lingers after treatment, has adverse effects on daily life, and predisposes to recurrence of depression. Yet, sensitive measures of executive function for reliable assessment of cognitive outcomes are still lacking in clinical practice. To better understand the impact of depression and its most effective treatment, electroconvulsive...