Mixed Mania Episode
Mixed episodes are defined by symptoms of mania and depression that occur at the same time or in rapid sequence without recovery in between.. Mania with mixed features usually involves irritability, high energy, racing thoughts and speech, and overactivity or agitation.Apr 14, 2020
Wiki Number: PW128
Diagnosis: Mixed Mania Episode
Symptoms: Both mania and depression features occur in rapid succession: ideas of suicide, homicide, sensory overload, heightened irrritability.
Progression: positive nervous energy is interspersed with depressive rumination along with exhaustion and purposeless movement.
Causes: Breaks up depression by adding in manic episodes while no manic episodes have occurred previously making it bipolar I or II.
Medications: Mood stabilizers; anticonvulsants; antipsychotics. These may quiet the mania, but not help much with depressive symptoms.
4 CURRENT ARTICLES
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PubMed article’s summary-abstract.
- Symptoms and Characteristics of Youth Hospitalized for Depression: Subthreshold Manic Symptoms Can Help Differentiate Bipolar from Unipolar Depressionby Anna Van Meter on October 12, 2021
Background: Most people who have major depressive disorder (MDD) or bipolar disorder (BD) will have their first episode of depression in adolescence. However, in the absence of significant [hypo]manic symptoms, there are no clear guidelines for distinguishing bipolar from unipolar depression, which can lead to misdiagnosis and ineffective/harmful treatment. We aimed to compare phenomenological differences among youth with MDD or BD hospitalized for an acute episode of depression. Methods: A...
- Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) recommendations for the management of patients with bipolar disorder with mixed presentationsby Lakshmi N Yatham on October 2, 2021
CONCLUSION: The CANMAT and ISBD groups hope these guidelines provide valuable support for clinicians providing care to patients experiencing mixed presentations, as well as further influence investment in research to improve diagnosis and treatment of this common and complex clinical state.
- Early intervention in bipolar affective disorders: Why, when and howby A Pouchon on September 27, 2021
CONCLUSIONS: EIS for psychosis might consider developing and implementing screening and treatment approaches for individuals experiencing an early stage of BD. Several opportunities for progress on early intervention in the early stages of BD can be drawn. Training first-line practitioners to identify at-risk subjects would be relevant to optimize screening of this population. Biomarkers including functional and structural imaging measures of specific cortical regions and inflammation proteins...
- Treatment of bipolar disorders in older adults: a reviewby Nemanja Ljubic on September 22, 2021
CONCLUSIONS: There is an obvious need of further research for all treatment modalities of BD in old age. The focus should be pharmacological and psychosocial approaches, as well as their combination, and the role of physical treatment modalities such as ECT.