Lacunar Amnesia

Lacunar amnesia is the loss of memory about a specific event. This specific form of amnesia is caused by brain damage in the limbic system which is responsible for our memories and emotions. When the damage occurs it leaves a lacuna, or a gap, in the record of memory within the cortex region of the brain.


Cluster Number:
Wiki Number: PW112
Diagnosis: Lacunar Amnesia
US Patients:
World Patients:
Sex Ratio:
Age Onset:
Brain Area: hippocampus -stores memories normally; amygdala as an emotional center may work short-term; memories may be blocked in PTSD
Symptoms: amnesia-loss of memory about a specific event;
Progression: Blocking a certain chemical (not named in the Wikipedia article) in rats can block learned behaviors
Causes: “lacuna” is a gap; a defensive blind spot; can be due to alcohol or drugs; may be temporary or permanent
Therapies: memories may be blocked in PTSD but no with explanation in the Wikipedia article


The world-wide medical research
reports chosen for each diagnosis 

Clicking each title opens the
PubMed article’s summary-abstract.

  • Retrograde amnesia with transposition in the past: A neuropsychological and PET study of a case
    by Dorothée Pouliquen on December 3, 2019

    CONCLUSION: The "transposition in the past" phenomenon illustrates the relationship between both episodic and autobiographical memories and the functioning of self, according to the SMS model. Moreover, this case suggests the involvement of the hippocampus in this phenomenon. (PsycINFO Database Record (c) 2020 APA, all rights reserved).

  • Acute global amnesia as an exclusive presenting symptom of thalamic infarct: a diagnostic challenge
    by J L Chico-Garcia on March 26, 2019

    CONCLUSION: The diagnosis of thalamic infarcts that begin exclusively with amnesia is very difficult and this has negative repercussions on their treatment in the acute phase. These infarcts can produce a functionally disabling memory deficit in a high percentage of patients.

  • A Case of Transient Global Amnesia with Small Left Putamen Infarction
    by Kosuke Yoshida on November 20, 2016

    A 67-year-old right-handed woman experienced a sudden anterograde and retrograde short-term memory deficit that recovered on the next day. Magnetic resonance imaging (MRI) showed a spotty high-intensity lesion in the left putamen in the diffusion-weighted and fluid-attenuated inversion recovery images. Transient global amnesia due to lacunar infarction of the left putamen was diagnosed. Transient global amnesia is characterized by a sudden onset of anterograde amnesia that disappears within 24...

  • Transient Global Amnesia After Cerebral Angiography With Iomeprol: A Case Report
    by Cristina Tiu on May 14, 2016

    Transient global amnesia is now considered a very rare complication of cerebral angiography. Various etiological mechanisms have been suggested to account for this complication, but no consensus has been reached yet. This case report documents one of the few reported cases of cerebral angiography-related transient global amnesia associated with magnetic resonance imaging (MRI) evidence of unilateral hippocampal ischemia, most probably as a consequence of a transient reduction in regional...