Caffeine-Induced Sleep Disorder
Caffeine-induced sleep disorder is a psychiatric disorder that results from overconsumption of the stimulant caffeine. Caffeine is one of the most widely consumed psychoactive drug, almost 90% of Americans consume some type of caffeine each day.
Wiki Number: W030
Diagnosis: Caffeine-Induced Sleep Disorder
US Patients: 90% Use it.
Brain Area: blocks addenosine receptors; Increases norepinephrine to increase blood flow-intensity
Symptoms: More than 2 cups – jittery;
Progression: 3-4 hour half-life; no coffee after six hours from sleep; long-term higher blood pressure; higher body weight, stomach
4 CURRENT ARTICLES
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- Acupuncture stimulation at HT7 as a non-pharmacological therapy for sleep disorder caused by caffeine administration in ratsby Su Yeon Seo on May 31, 2021
CONCLUSION: These results indicate that the hypnotic effect of HT7 acupuncture stimulation on caffeine-induced insomnia was associated with suppression of neuronal activity in the basal forebrain.
- Fermented Gamma Aminobutyric Acid Improves Sleep Behaviors in Fruit Flies and Rodent Modelsby A-Hyun Jeong on April 3, 2021
The aim of this study was to investigate the effect of Lactobacillus brevis-fermented γ-aminobutyric acid (LB-GABA) on sleep behaviors in invertebrate and vertebrate models. In Drosophila melanogaster, LB-GABA-treated group showed an 8-9%-longer sleep duration than normal group did. LB-GABA-treated group also showed a 46.7% lower level of nighttime activity with a longer (11%) sleep duration under caffeine-induced arousal conditions. The LB-GABA-mediated inhibition of activity was confirmed as a...
- A Standardized Phlorotannin Supplement Attenuates Caffeine-Induced Sleep Disruption in Miceby Sangoh Kwon on March 9, 2019
In our previous studies, a standardized phlorotannin (brown seaweed polyphenol) supplement (PS) exhibited sleep-promoting effects via type A γ-aminobutyric acid-benzodiazepine receptors in mice. In addition, in human clinical trials, it decreased wake after sleep onset in adults with sleep disturbance. In this follow-up study, we investigated whether PS attenuates caffeine-induced sleep disruption in mice. The effects of PS were evaluated in a caffeine model by analyzing sleep architecture based...
- Endogenous Nitric Oxide Inhibits, Whereas Awakening Stimuli Increase, the Activity of a Subset of Orexin Neuronsby Takao Yamakawa on December 4, 2018
The lateral hypothalamic area contains neurons expressing neuronal nitric oxide synthase (nNOS), in addition to orexin neurons. Here we examined whether the activity of orexin neurons was regulated by endogenous nitric oxide (NO) in male C57BL/6 mice. Caffeine (30 mg/kg, intraperitoneally (i.p.)) increased the number of orexin neurons positive for c-Fos, a marker of neuronal activity, and also increased the number of NOS/c-Fos-positive cells as identified by reduced nicotinamide adenine...